Hydrogen Peroxide Insular Dodecameric and Pentameric Clusters in Peroxosolvate Structures. Issue 48 (19th October 2017)

• Record Type: Journal Article
• Authors: Grishanov, Dmitry A.; Navasardyan, Mger A.; Medvedev, Alexander G.; Lev, Ovadia; Prikhodchenko, Petr V.; Churakov, Andrei V.
• Is Part Of: Angewandte Chemie international edition. Volume 56:Issue 48(2017)
• Page Start: 15241
• Page End: 15245
• Publication Date: 2017-10-19
• Subjects: cluster compounds -- hydrogen bonds -- hydrogen peroxides -- structure elucidation -- supramolecular chemistry; Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201709699
• Languages: English
• ISSNs: 1433-7851

Abstract

Abstract: Peroxosolvates of 2‐aminonicotinic acid (I ) and lidocaine N ‐oxide (II ) including the largest insular hydrogen peroxide clusters were isolated and their crystal structures were determined by single‐crystal X‐ray diffraction. An unprecedented dodecameric hydrogen peroxide insular cluster was found inI . An unusual cross‐like pentameric cluster was observed in the structure ofII . The topology of the (H2 O2 )12 assembly was never observed for small‐molecule clusters. InI andII new double and triple cross‐orientational disorders of H2 O2 were found. ClusterII is the first example of a peroxosolvate crystal structure containing H2 O2 molecules with a homoleptic hydrogen peroxide environment. InII, a hydrogen bond between an H2 O2 molecule and a peptide group ‐CONH⋅⋅⋅O2 H2 was observed for the first time. Abstract : Peroxide bond : Peroxosolvates of 2‐aminonicotinic acid (I ) and lidocaine N ‐oxide (II ) including unprecedented dodecameric and pentameric discrete hydrogen peroxide clusters were isolated and their structures were determined by single‐crystal X‐ray diffraction. InI andII new double and triple cross‐orientational disorders of H2 O2 were found. InII, a hydrogen bond between an H2 O2 molecule and a peptide group was observed for the first time.