The effects of aminosalicylates or thiopurines on the risk of colorectal cancer in inflammatory bowel disease. Issue 4 (19th December 2016)

• Record Type: Journal Article
• Authors: Carrat, F.; Seksik, P.; Colombel, J.‐F.; Peyrin‐Biroulet, L.; Beaugerie, L.
• Other Names: Colombel Jean‐Frédéric investigator.; Cosnes Jacques investigator.; Gendre Jean‐Pierre investigator.; Lémann Marc investigator.; Hébuterne Xavier investigator.; Cortot Antoine investigator.; Bouhnik Yoram investigator.; Laharie David investigator.; Dupas Jean Louis investigator.; Flourié Bernard investigator.; Lerebours Eric investigator.; Beaugerie Laurent investigator.; Peyrin‐Biroulet Laurent investigator.; Allez Matthieu investigator.; Messing Bernard investigator.; Cadiot Guillaume investigator.; Marteau Philippe investigator.; Soulé Jean‐Claude investigator.; Gornet Jean‐Marc investigator.; Veyrac Michel investigator.; Duclos Bernard investigator.; Beau Philippe investigator.; Bourreille Arnaud investigator.; Baumer Philippe investigator.; Carbonnel Franck investigator.; Heresbach Denis investigator.; Metman Etienne‐Henry investigator.; Florent Christian investigator.; Blain Antoine investigator.; Faucheron Jean‐Luc investigator.; Bonaz Bruno investigator.; Roblin Xavier investigator.; Potier Pascal investigator.; Boehm Christian investigator.; Kurtz Thierry investigator.; Lamouliatte Hervé investigator.; Nion‐Larmurier Isabelle investigator.; Delchier Jean‐Charles investigator.; Chaussade Stanislas investigator.; Weiss Anne Marie investigator.; Cézard Jean Pierre investigator.; Siproudhis Laurent investigator.; Nahon Stéphane investigator.; Sondag Daniel investigator.; Jian Raymond investigator.; Souquet Jean‐Christophe investigator.; Bord Pierre investigator.; Coffin Benoit investigator.; D'almagne Hélène investigator.; Delasalle Patrick investigator.; Fournier Régis investigator.; Cavicchi Maryan investigator.; Souffran Marc‐Henry investigator.; Vandromme Luc investigator.; Guedon Claire investigator.; Seksik Philippe investigator.; Michiels Christophe investigator.; Renard Pascal investigator.; Rogier Patrice investigator.; Gouilloud Sylvie investigator.; Rotenberg André investigator.; Savoye Guillaume investigator.; Thevenin Alain investigator.; Mallet Laurent investigator.; Brazier Franck investigator.; Jean Francois investigator.; Justum Anne‐Marie investigator.; Latrive Jean‐Paul investigator.; Gerbal Jean‐Luc investigator.; Pierrugues Robert investigator.; Chardonnal Gérard investigator.; Picon Laurence investigator.; Reix Nicole investigator.; D'aubigny Nicolas Drouët investigator.; Uettwiller Hervé investigator.; Mallet Anne Courillon investigator.; Palacci Alain investigator.; Bensaude Raoul‐Jacques investigator.; Bonniaud Pierre investigator.; Empinet Olivier investigator.; Nisard Andrée investigator.; Rudelli Alain investigator.; Tubiana Bernard investigator.; Capelle Philippe investigator.; Dabadie Alain investigator.; Evard Daniel investigator.; Julien Pierre‐Emile investigator.; Picon‐Coste Magali investigator.; Schneider Stéphane investigator.; Goldfain Denis investigator.; Bellanger Jérôme investigator.; Blondelot Jean‐Pierre investigator.; Lamy Philippe investigator.; Lemière Sébastien investigator.; Mockly Jean Francois investigator.; Pellat Benoit investigator.; Gatineau‐Sailliant Gilles investigator.; Nalet Bernard investigator.; Nancey Stéphane investigator.; Kusielewicz Daniel investigator.; Loison Patrick investigator.; Popot Jean‐Michel investigator.; Merite François investigator.; Roux Jean‐Pol investigator.; Afchain Pauline investigator.; Blanquart Alain investigator.; Heyries Laurent investigator.; Reville Marc investigator.; Viron Dominique investigator.; Zerbib Frank investigator.; Claviere Christophe investigator.; Léostic Didier investigator.; Pouderoux Philippe investigator.; Moitry Alain investigator.; Hagège Hervé investigator.; Hugot Jean‐Pierre investigator.; Humeau Benoit investigator.; Sabate Jean‐Marc investigator.; Lederman Emmanuel investigator.; Lescut Dominique investigator.; Luneau Fabrice investigator.; Mesnard Bruno investigator.; Smadja Lionel investigator.; Steinberg Michel investigator.; Brun Marc investigator.; Macaigne Gilles investigator.; Marchal Jean Luc investigator.; Ollivier Stéphane investigator.; Ouvry Dominique investigator.; Perche Jean Paul investigator.; Rambaud Serge investigator.; Benamouzig Robert investigator.; Cazenave Jean Louis investigator.; Coffin Jean‐Charles investigator.; Blazquez Martine investigator.; Lagneau Marion investigator.; Person Bruno investigator.; Wittersheim Christian investigator.; Napoleon Bertrand investigator.; Cemachovic Israël investigator.; Iglicki Franck investigator.; Howaizi Mehran investigator.; Leprince Eric investigator.; Leurent Bruno investigator.; Morin Thierry investigator.; Darsouni Riad investigator.; Attar Alain investigator.; Baron Philippe investigator.; Breton Anne investigator.; Gillion Jean Marie investigator.; Guemene Jean‐Marc investigator.; Jouffre Claude investigator.; Moreau Xavier investigator.; Claude Pierre investigator.; Quinton André investigator.; Abitbol Vered investigator.; Brichard Jean Michel investigator.; Desaint Benoit investigator.; Bouygues Martin investigator.; Chatrenet Philippe investigator.; Salmeron Marcelo investigator.; Silvie Jean investigator.; Waldner Bruno investigator.; Emery Yves investigator.; Moraillon Armand investigator.; Kunkel Daniel investigator.; Dubois Philippe investigator.; Faure Patrick investigator.; L'Hirondel Christian investigator.; Labérenne Jean‐Eric investigator.; Moreau Pierre investigator.; Pereira Adelino investigator.; Plihon Genevieve investigator.; Wolff Thierry investigator.; Ngo Yann investigator.; Boruchowicz Arnaud investigator.; Jost Béatrice investigator.; Gotlib Jean Pierre investigator.; Danne Odile investigator.; Raoux Philippe investigator.; Ramond‐Bouhali Marie‐José investigator.; Baetz Andre investigator.; Veyres Bruno investigator.; Chapoutot Christian investigator.; Le Dréau Gérard investigator.; Filippi Jérôme investigator.; Mudry Jean investigator.; Kalt Philippe investigator.; Minault Sophie investigator.; Bounin Pierre‐André investigator.; Andréani Tony investigator.; Charneau Jacky investigator.; Reijasse Didier investigator.; Bolze Jean‐Louis investigator.; Thaunat Jean Luc investigator.; Le Couteulx Christian investigator.; Maurage Chantal investigator.; Bader Robert investigator.; Codjovi Philippe investigator.; Migairou Jean‐Luc investigator.; Morali Alain investigator.; Rey Philippe investigator.; Molard Bruno Richard investigator.; Petit Richard investigator.; Koch; Stéphane investigator.; Cassan Philippe investigator.; Deschamps Jean‐Paul investigator.; Caby Christine Meicler investigator.; Meurisse Jean‐Jacques investigator.; Prades Philippe investigator.; Boulant James investigator.; Diacono Michel investigator.; Monsch Jean‐Marie investigator.; Dupuy J‐François investigator.; Bellaiche Guy investigator.; Guegan Martine investigator.; Comte Jean‐Marc investigator.; Cayla Jean‐Michel investigator.; Le Tallec Francois investigator.; Meurisse Franck investigator.; Desurmont Philippe investigator.; Roget Laurent investigator.; Bouyssou Philippe investigator.; Le Gall Bruno investigator.; Bloch Francis investigator.; Larvol Loic investigator.; Jullien Monique investigator.; Moreau Jacques investigator.; Rebouissoux Laurent investigator.; Decroix Bruno investigator.; Dib Nina investigator.; Dieterling Paul investigator.; Lenormand Frédéric investigator.; Lagier Emmanuel investigator.; Fallourd Philippe investigator.; Charpin Serge investigator.; Bertrand Hugues investigator.; Bommelaer Gilles investigator.; Battistelli Daniel investigator.; Delon Bernard investigator.; Dentant Lionel investigator.; Dorval Etienne investigator.; Dumortier Jérôme investigator.; Gaye‐Bareyt Eric investigator.; Gerosa Yves investigator.; Guez Chantal investigator.; Mornet Martine investigator.; Benfredj Paul investigator.; Piperaud René investigator.; Stremsdoerfer Noel investigator.; Verdier Eric investigator.; Grinholtz Alain investigator.; Barjonet Georges investigator.; See Antoine investigator.; Arotçarena Ramuntxo investigator.; Baudet Anne investigator.; Broyer Joel investigator.; Charachon Antoine investigator.; Blondon Hugues investigator.; Mouton Pascal investigator.; Claudez Hubert investigator.; Labat‐Labourdette Jacques investigator.; Haëm Jacques investigator.; Estable Patrick investigator.; Levy Patrick investigator.; Rosenbaum Alain investigator.; Balavoine Yvon investigator.; Blanchi Alain investigator.; Coutarel Pierre investigator.; Delaperriere Nadege investigator.; Dervichian Michel investigator.; Marois Francis investigator.; Seroka Jacques investigator.; Michaud Laurent investigator.; Leroy Olivier investigator.; Meyran Emmanuel investigator.; Poilroux Bernard investigator.; Tensaouti Abdallah investigator.; Paupard Thierry investigator.; Agard Dominique investigator.; Beaulieu Sandrine investigator.; Benfiguig Kader investigator.; Capony Patrice investigator.; Cottereau Jean investigator.; Desreumaux Pierre investigator.; Dramard Jean‐Michel investigator.; Duché Mathieu investigator.; Mamou Patrick investigator.; Etienney Isabelle investigator.; D'Abrigeon Gilles investigator.; Godeberge Béatrice investigator.; Tucat Gilbert investigator.; Puech Jean investigator.; Roger Jean investigator.; Lapalus Marie‐George investigator.; Bauret Paul investigator.; Houcke Philippe investigator.; Pornin Béatrice investigator.; Champigneulle Bruno investigator.; Cuissard Laurent investigator.; David Xavier‐Richard investigator.; Lombard Frédéric investigator.; Granveau Antoine investigator.; Hamon Jean‐François investigator.; Ink Olivier investigator.; Blondel Fabienne investigator.; Namias Alain investigator.; Pillon Didier investigator.; Reignier Antoine investigator.; Tordjman Gilles investigator.; Christidis Christos investigator.; Zirabe Simon investigator.; Audebert Michel investigator.; Bion Eric investigator.; Bourgeaux Claude investigator.; Poupardin Cécile investigator.; Deplaix Philippe investigator.; Fratini Gérard investigator.; Garnier Thierry investigator.; Desseaux Gerard investigator.; Magois Hervé investigator.; Lochum Sylvain investigator.; Vergier Jean‐Francois investigator.; Texereau Patrick investigator.; Rat Christel investigator.; Uzzan Francoise investigator.; Vidal Alain investigator.; Vinante Nadia investigator.; Watrin Bernard investigator.; Wurtz‐Huckert Cécile investigator.; Barre Bruno investigator.; Ferbus Dominique Chaslin investigator.; Contou Jean‐François investigator.; Coupier Dominique investigator.; David Benoit investigator.; Gargot Dany investigator.; Huc Denis investigator.; Barraya Remy investigator.; Faroux Roger investigator.; Fourgeaud Jean‐Luc investigator.; Grimprel Hubert investigator.; Auroux Jean investigator.; Rey Jean‐François investigator.; Arnoux Jean Pierre investigator.; Lentini Franck investigator.; Tardy Ludovic investigator.; Mouterde Olivier investigator.; Spyckerelle Claire investigator.; Vacherot Bruno investigator.; Weissman Alain investigator.; Alpérine Michel investigator.; Le Sidaner Anne investigator.; Bonnet‐Eymard Pierre‐Olivier investigator.; Colson Jean Louis investigator.; Pellet Daniel investigator.; Deltombe Bernard investigator.; Edouard André investigator.; Maechel Henri investigator.; Jaillet Jean‐Claude investigator.; Genes Julien investigator.; Leveque Anne‐Marie investigator.; Lucidarme Damien investigator.; Maignan Philippe investigator.; Gehrke Nathalie Mallier investigator.; Sanchez Jérôme investigator.; Tusseau Frank investigator.; Casteur Alban investigator.; Bottlaender Jacques investigator.; Constantini Denis investigator.; Coton Thierry investigator.; Even Philippe investigator.; Druart Francois investigator.; Riot François investigator.; Gauchet Jean‐Michel investigator.; Hecquet Geneviève investigator.; Henry Gerard investigator.; Hochain Patrick investigator.; Arpurt Jean Pierre investigator.; Medini Abdelkrim investigator.; Dartois‐Hoguin Michele investigator.; Moindrot Henri investigator.; Emery Philippe investigator.; Periac Pierre investigator.; Prunier Annie investigator.; Renkes Pascal investigator.; Tawil‐Longreen Christine investigator.; Vincent Edmond investigator.; Vitte René‐Louis investigator.; Loeb Christian investigator.; Carwana Alain investigator.; Barbereau Didier investigator.; Bohon Philippe investigator.; Corrieri‐Baizeau Céline investigator.; Sahy Daniel investigator.; Derreveaux Philippe investigator.; David Dominique investigator.; Desbazeille François investigator.; Fontenelle Patrick investigator.; Slama Jean Luc investigator.; Le Mercier Yvon investigator.; Certin Michel investigator.; Reig Jean Jacques investigator.; Rosa Isabelle investigator.; Helbert Thierry investigator.; Tounian Patrick investigator.; Turner Luc investigator.; Perot Valéry investigator.; Aillet Luc investigator.; Pauwels Arnaud investigator.; Barré Philippe investigator.; Nury Bernard investigator.; Cazalbou Claude investigator.; Devulder Franck investigator.; Durget Alain investigator.; Dubroca Jeanne investigator.; Gaudy Daniele investigator.; Greff Michel investigator.; Jacques Christian investigator.; Lafarge Jocelyne investigator.; Kezachian Gilles investigator.; Le Gall Ronan investigator.; Pariente Alex investigator.; Pinault Tiphaine investigator.; Bismuth Michaël investigator.; Boyer‐Darrigrand Nathalie investigator.; Bretagnolle Philippe investigator.; Carpentier Stephane investigator.; Cholet Franck investigator.; Theodore Christian investigator.; Combes Rémi investigator.; Combet Francois investigator.; Delanoe Christophe investigator.; De Montigny Stéphanie investigator.; Soudan Denis investigator.; Fourdan Olivier investigator.; Minier Gilles investigator.; Languepin Jeanne investigator.; Roche Jean investigator.; Ginies Jean‐Louis investigator.; Nouel Olivier investigator.; Petitgars Philippe investigator.; Robin Edith investigator.; Hamm Romain investigator.; Roques Jean François investigator.; Roussin‐Bretagne Sylvie investigator.; Sénéjoux Agnès investigator.; Muron Sophie investigator.; Bardoux Nicolas investigator.; Berthelemy Philippe investigator.; Madonia Patrick investigator.; Carles Bertrand investigator.; Reynier Catherine investigator.; Cuillerier Emmanuel investigator.; Dadamessi Innocenti investigator.; Danis Jacques investigator.; Debenes Bernard investigator.; Dubuc‐Rey Nathalie investigator.; Lesur Gilles investigator.; Jouet Pauline investigator.; Lenaerts Catherine investigator.; Garret Marc investigator.; Mineur Alexandra investigator.; Chabry Bernard investigator.; Pigot Francois investigator.; Rossi Valérie investigator.; Tennenbaum Ruth investigator.; Salloum Julien investigator.; Slaoui Maurice Hakim investigator.; Mathieu Stéphane investigator.; Papapietro Valérie investigator.; Viola Sheila investigator.; Bezet Alexis investigator.; Altman Claude investigator.; Audan Alain investigator.; Calabet Jean investigator.; Masliah Claude investigator.; Fayemendy Laurent investigator.; Duruy Marc investigator.; Gauffeny Benoit investigator.; Helie Ludovic investigator.; Imani Kamran investigator.; Janin‐Manificat Raoul investigator.; Galmiche Jean‐Paul investigator.; Kerlirzin Anne investigator.; Bedenne Laurent investigator.; Locher Christophe investigator.; Michaudel Gilles investigator.; Missonnier Gilles investigator.; Rinaldi‐Dovio Michel investigator.; Rouillon Jean‐Michel investigator.; Ecuer Stéphane investigator.; Patenotte Arnaud investigator.; Bronstein Jean Ariel investigator.; Baty Vincent investigator.; Bougnol Michel investigator.; Bourbon Pierre investigator.; Cerbelaud Philippe investigator.; Chavaillon Annick investigator.; Boiffin Franck investigator.; Dubern Béatrice investigator.; De Laguierce Isabelle Duval investigator.; Greco Fernand investigator.; Bouhot Florence investigator.; Godeberge Philippe investigator.; Grandmaison Brigitte investigator.; Gros Pascal investigator.; Targues Guy investigator.; Corallo Jacques investigator.; Boutin Jean investigator.; Guillan Jacques investigator.; Barbieux Jean Pierre investigator.; Lariviere Isabelle Loury investigator.; Le Genissel Henri investigator.; Leroi Henri investigator.; Bellaiche Marc investigator.; Elie‐Legrand Marie‐Claire investigator.; Dapoigny Michel investigator.; Denoyel Philippe investigator.; Pienkowski Patrice investigator.; Pouche Philippe investigator.; Saurfelt Marc Michel investigator.; Thorel Jean Marie investigator.; Piche Thierry investigator.; Travers Bruno investigator.; Tuvignon Patrick investigator.; Zalcberg Marc investigator.; Boulay Guy investigator.; Zamora Christophe investigator.; Samama Joelle investigator.; Ricotie Etienne investigator.; De Fleury Patrice investigator.; Maille Francois investigator.; Mougenel Jean Louis investigator.; Gonot Olivier investigator.; Menat Jean Philippe investigator.; Kaassis Mehdi investigator.; Lang Francoise investigator.; Abramowitz Laurent investigator.; Ganne Nathalie investigator.; Pecriaux Olivier investigator.; Seyrig Jacques‐Arnaud investigator.; Sobhani Iradj investigator.; Parmentier Thierry investigator.; Van Nieuwenhuyse Antoine investigator.; Weber Francois‐Xavier investigator.; Glibert André investigator.; Bineau Catherine investigator.; Canet Bernard investigator.; Collin Catherine investigator.; Cordet Frederic investigator.; Parlier David David investigator.; Carre Dominique investigator.; Peytier Annie investigator.; Fein Francine investigator.; Barouk Jerome investigator.; Dewannieux Jacques investigator.; Hartwig Johannes investigator.; Jouve Jean‐Louis investigator.; Laplane Bertrand investigator.; Lascar Gilles investigator.; Legrand Christophe investigator.; Le Marchand Pierre investigator.; Liebaert Marie Pierre investigator.; Terdiman‐Pire Michele investigator.; Abdelli Naceur investigator.; Neveu Dominique investigator.; De La Lande Philippe investigator.; De Saint Louvent Patrick investigator.; Pelatan Cécile investigator.; Petit Agnès investigator.; Richecoeur Martial investigator.; Texier Frederic investigator.; Cazals Jean Brice investigator.; Tissot Bertrand investigator.; Mourrut Christian investigator.; Doubremelle Marie investigator.; Foltz Marc investigator.; Gautier‐Jubé Florence investigator.; Martin Jacques investigator.; Khouri Elie investigator.; Lons Thierry investigator.; Carlier‐Bandu Martine investigator.; Monnin Jean‐Luc investigator.; Roche Hervé investigator.; Willemin Bernard investigator.; Houard Xavier investigator.; Fatisse Abdelaziz investigator.; Algard Michèle investigator.; Arab Kamel investigator.; Borel Isabelle investigator.; Lagarrigue Cécile investigator.; Chryssostalis Ariane investigator.; Boutroux Dominique investigator.; Dupuychaffray Jean‐Pierre investigator.; Khaddari Saïd investigator.; Mion François investigator.; Puy‐Montbrun Thierry investigator.; Girardet Jean‐Philippe investigator.; Gury Bruno investigator.; Landau Alain investigator.; Le Bihan Monique investigator.; Nieuviarts Sandrine investigator.; Ollivry Jean investigator.; Le Bourgeois Philippe investigator.; Piquet Marie‐Astrid investigator.; Escartin Michel ‐Pierre investigator.; Systchenko Remi investigator.; Venezia Franck investigator.; Wantiez Michel investigator.; Lesage Xavier investigator.; Zrihen Elie investigator.; Aygalenq Philippe investigator.; Dieumegard Barbara investigator.; Savarieau Bernard investigator.; Bulois Philippe investigator.; Cattan Stéphane investigator.; Diez Jean‐Lucien investigator.; Fauchot Olivier investigator.; Durous Eric investigator.; Gazut Valérie investigator.; Guilleminet Christian investigator.; Bories Jean‐Marc investigator.; Le Floch Isabelle Joly investigator.; Vove Jean‐Paul investigator.; Lelouch Stéphane investigator.; Lévy Philippe investigator.; Lhopital François investigator.; Marcato Norma investigator.; Mozer‐Bernardeau Marianne investigator.; Nousbaum Jean‐Baptiste investigator.; Cattan Philippe investigator.; Plane Alain investigator.; Raymond Jean‐Michel investigator.; Roseau Gilles investigator.; Rozental Gerald investigator.; Boustière Christian investigator.; Bonny Corinne investigator.; Cordier‐Collet Mariepierre investigator.; Courat Laurent investigator.; Croguennec Bernard investigator.; Delaunay‐Tardy Karine investigator.; Labarriere Damien investigator.; Geagea Edmond investigator.; Gottrand Frédéric investigator.; Gelsi Eve investigator.; Thiefin Gerard investigator.; Wohlschies Eric investigator.; Miguet Mathieu investigator.; Ponsot Philippe investigator.; Suzanne Jean investigator.; Teste Yves investigator.; Gossart Anne‐Claire Dupont investigator.; Baroni Jean‐Luc investigator.; Benchaa Benabdallah investigator.; Blanc Georges investigator.; Maroy Bernard investigator.; Bonjean Philippe investigator.; Brézault Catherine investigator.; Bridoux‐Henno Laure investigator.; Chayette Claude investigator.; Auby Dominique investigator.; Fiorucci Robert investigator.; Galindo Georges investigator.; Hubert Gilles investigator.; Bonneau Gilles investigator.; Marinier Evelyne investigator.; Pouteau Michele investigator.; Alamdari Afchine investigator.; Delbende Bruno investigator.; Chamouard Patrick investigator.; D'Abravanel Pascale investigator.; Dall'Osto Hélène investigator.; Hervé Sophie investigator.; Lefebvre Jean investigator.; Levoir Damien investigator.; Lillo Philippe investigator.; Rouch Michel investigator.; Mathonnet Muriel investigator.; De Lustrac Mercédes investigator.; Ramond François‐Jean investigator.; Roupret Bernard investigator.; Soupison Alain investigator.; Ait‐Ouadda Djamila investigator.; Barbaza Yves investigator.; Bayart Brice investigator.; Bottini Thomas investigator.; Cochet Franck investigator.; Goderel Isabelle investigator.; Maury Orélien investigator.; Mbonyingo Léa investigator.; Pourtau Vanessa investigator.; Rasoanarivo Elise investigator.; Romain‐Huttin Laure investigator.; Sallé Anne‐Violaine investigator.; Trang Jonathan investigator.; Admane Hakeem investigator.; Drouet Elodie investigator.;
• Is Part Of: Alimentary pharmacology & therapeutics. Volume 45:Issue 4(2017)
• Page Start: 533
• Page End: 541
• Publication Date: 2016-12-19
• Subjects: Digestive organs -- Diseases -- Treatment -- Periodicals; Digestive organs -- Effect of drugs on -- Periodicals; Gastrointestinal system -- Diseases -- Treatment -- Periodicals; Gastrointestinal system -- Effect of drugs on -- Periodicals; 615.73
• DOI: 10.1111/apt.13897
• Languages: English
• ISSNs: 0269-2813

Abstract

Summary: Background: Whether aminosalicylates or thiopurines reduce the risk of colorectal cancer (CRC) in inflammatory bowel (IBD) disease is controversial. Aim: To assess simultaneously the chemopreventive effect of aminosalicylates or thiopurines in a case–control study nested in the CESAME observational cohort that enrolled consecutive patients with IBD between May 2004 and June 2005. Patients were followed up to December 2007. Methods: Study population comprised 144 case patients who developed CRC from the diagnosis of IBD (65 and 79 cases diagnosed, respectively, before and from 2004, starting year of the prospective observational period of CESAME) and 286 controls matched for gender, age, IBD subtype and year of diagnosis, and cumulative extent of colitis. Exposure to aminosalicylates or thiopurines was defined by an exposure to the treatment during the year of the diagnosis of cancer. The propensity of receiving 5‐ASA and thiopurines was quantified by a composite score taking into account patient and IBD characteristics. The role of aminosalicylates or thiopurines was assessed by multivariate analysis. Propensity scores and the history of primary sclerosing cholangitis were entered into the multivariate model for adjustment. Results: By multivariate analysis adjusted for propensity, a significant protective effect of exposure to drugs during the year of cancer was found for aminosalicylates (OR = 0.587, 95% CI: 0.367–0.937, P = 0.0257), but not for thiopurines (OR = 0.762, 95% CI: 0.432–1.343, P = 0.3468). Conclusion: In a case–control study nested in the CESAME cohort, a significant decrease in the risk of colorectal cancer in IBD was associated with exposure to aminosalicylates, not to thiopurines.