ScCVD Diamond Membrane based Microdosimeter for Hadron Therapy. Issue 22 (30th July 2018)
- Record Type:
- Journal Article
- Title:
- ScCVD Diamond Membrane based Microdosimeter for Hadron Therapy. Issue 22 (30th July 2018)
- Main Title:
- ScCVD Diamond Membrane based Microdosimeter for Hadron Therapy
- Authors:
- Zahradnik, Izabella A.
Pomorski, Michal T.
De Marzi, Ludovic
Tromson, Dominique
Barberet, Philippe
Skukan, Natko
Bergonzo, Philippe
Devès, Guillaume
Herault, Joël
Kada, Wataru
Pourcher, Thierry
Saada, Samuel - Other Names:
- May Paul W. guestEditor.
Pobedinskas Paulius guestEditor.
Nicley Shannon S. guestEditor. - Abstract:
- Abstract : Hadron therapy is an innovative mode of radiotherapy (RT) for cancer treatment which enables tumor cells to be more effectively destroyed than conventional RT using photons. The precise knowledge of the lineal energy of particles is used in the field of microdosimetry (MKM model) as a fundamental parameter in the prediction of the relative biological efficiency (RBE) of clinical beams. Based on single‐crystal CVD (scCVD) super‐thin diamond membranes obtained using deep Ar/O2 plasma etching, prototypes of solid‐state microdosimeters for lineal energy measurements are produced at the Diamond Sensors Laboratory of CEA‐LIST. The response of a diamond membrane microdosimeter to single projectiles is investigated in ion microbeams. The microdosimeter is irradiated using a raster scanning method and the charge transport properties of the device are determined with sub‐micron precision by measuring the charge collection efficiency (CCE), the μSVs 3D spatial definition and the pulse‐height spectra. A prototype of this novel microdosimeter is then tested in a 100 MeV therapeutic proton beam at the Institute Curie − Proton Therapy Centre in Orsay. All results effectively demonstrate the great potential for this device to be used for studies of the RBE in clinical applications. Abstract : Active micro‐sensitive volumes (μSVs) of the tested scCVD diamond membrane based microdosimeter. The colored pixels represent detected ion hits (interactions/pixel) during the ion beamAbstract : Hadron therapy is an innovative mode of radiotherapy (RT) for cancer treatment which enables tumor cells to be more effectively destroyed than conventional RT using photons. The precise knowledge of the lineal energy of particles is used in the field of microdosimetry (MKM model) as a fundamental parameter in the prediction of the relative biological efficiency (RBE) of clinical beams. Based on single‐crystal CVD (scCVD) super‐thin diamond membranes obtained using deep Ar/O2 plasma etching, prototypes of solid‐state microdosimeters for lineal energy measurements are produced at the Diamond Sensors Laboratory of CEA‐LIST. The response of a diamond membrane microdosimeter to single projectiles is investigated in ion microbeams. The microdosimeter is irradiated using a raster scanning method and the charge transport properties of the device are determined with sub‐micron precision by measuring the charge collection efficiency (CCE), the μSVs 3D spatial definition and the pulse‐height spectra. A prototype of this novel microdosimeter is then tested in a 100 MeV therapeutic proton beam at the Institute Curie − Proton Therapy Centre in Orsay. All results effectively demonstrate the great potential for this device to be used for studies of the RBE in clinical applications. Abstract : Active micro‐sensitive volumes (μSVs) of the tested scCVD diamond membrane based microdosimeter. The colored pixels represent detected ion hits (interactions/pixel) during the ion beam induced charge − IBIC − collection study at AIFIRA facility in CENBG, Bordeaux in France. … (more)
- Is Part Of:
- Physica status solidi. Volume 215:Issue 22(2018)
- Journal:
- Physica status solidi
- Issue:
- Volume 215:Issue 22(2018)
- Issue Display:
- Volume 215, Issue 22 (2018)
- Year:
- 2018
- Volume:
- 215
- Issue:
- 22
- Issue Sort Value:
- 2018-0215-0022-0000
- Page Start:
- n/a
- Page End:
- n/a
- Publication Date:
- 2018-07-30
- Subjects:
- diamond microdosimeter -- hadron therapy -- ion beam induced charge -- lineal energy -- microdosimetry -- micro‐sensitive volumes
Solid state physics -- Periodicals
Solids -- Industrial applications -- Periodicals
530.41 - Journal URLs:
- http://onlinelibrary.wiley.com/ ↗
- DOI:
- 10.1002/pssa.201800383 ↗
- Languages:
- English
- ISSNs:
- 1862-6300
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 6475.210000
British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 8626.xml