Internal Morphological Effects of Growth Hormone Transgenesis in Coho Salmon. Issue 6 (29th September 2018)

• Record Type: Journal Article
• Authors: Gaffney, L. P.; Watson, B. M.; Oakes, J. D.; Devlin, R. H.
• Is Part Of: Transactions of the American Fisheries Society. Volume 147:Issue 6(2018)
• Page Start: 1199
• Page End: 1206
• Publication Date: 2018-09-29
• Subjects: Fish culture -- Periodicals; Fishery management -- Periodicals; Pisciculture -- Périodiques; 639.2
• DOI: 10.1002/tafs.10118
• Languages: English
• ISSNs: 0002-8487

Abstract

Abstract: Effects of growth hormone (GH) overexpression on internal morphology were examined in homozygous and hemizygous GH transgenic Coho Salmon Oncorhynchus kisutch aided by clearing and staining and magnetic resonance imaging methodologies. Morphological effects of transgenesis were observed in pin bones in fast‐growing hemizygous transgenic salmon, in vertebral column and swim bladder deformities in homozygotes, and as nonproportional modifications to some cranial structures examined among groups. These data provide further examples of the complex pleiotropic effects arising from GH overexpression in transgenic salmon.