Variation in human vertebral body strength for vertebral body samples from different locations in segments L1–L5. (December 2018)

• Record Type: Journal Article
• Authors: Ogurkowska, M.B.; Błaszczyk, A.
• Is Part Of: Clinical biomechanics. Volume 60(2018)
• Page Start: 66
• Page End: 75
• Publication Date: 2018-12
• Subjects: Lumbar vertebrae -- Mechanical strength -- Destructive stress; Biomechanics -- Periodicals; Osteopathic medicine -- Periodicals; Biomechanics -- Periodicals; Osteopathic Medicine -- Periodicals; 612.76
• DOI: 10.1016/j.clinbiomech.2018.10.008
• Languages: English
• ISSNs: 0268-0033

Abstract

Abstract: Background: The human spine, in particular the lumbar spine, is subject to significant compressive and bending stresses, which affect the structure of the bone tissue of the vertebrae. The more heterogeneous the structure of the spongy bone tissue, the less resistant the whole vertebral body. It is therefore necessary to establish variations in bone strength parameters within one particular vertebral body. Methods: The research material comprised human L1–L5 lumbar vertebrae sampled from 15 donors aged 29–35. A total of 975 samples prepared from the collected material were subjected to compressive and bending strength tests. The samples for the tests were collected from carefully selected locations in order to discover the strength properties of various parts of the vertebral body. Findings: In the case of sample 2 (located in the posterior part of the vertebra, at mid-height) the stress values were the lowest and there were statistically significant differences compared to other samples. Moreover the value of compressive force in this case was lower for vertebrae with higher numbers. Top and bottom samples demonstrated statistically significant higher mean values of destructive stress. In terms of the bending strength test, the mean value of destructive stress in all lumbar vertebrae for all samples increased for vertebrae with higher numbers. Interpretation: The spongy tissue in healthy vertebral bodies has a very heterogeneous structure. This may be due to the presence of the nutrient canal and the arc structure allowing more springy movement and improved transfer of loads by the vertebral body. Highlights: Poor structural integrity of cancellous bone may lead to insufficient load cushioning and cause fractures. Spongy bone tissue in a single vertebra differs in terms of compression strength. Spongy bone tissue closest to the vertebral canal has lowest resistance to compression. Spongy bone tissue strength properties increase for vertebrae with higher numbers. Strength properties values of different areas of cancellous bone allow to create more accurate models of the spine.