Beneficial postprandial lipaemic effects of interrupting sedentary time with high-intensity physical activity versus a continuous moderate-intensity physical activity bout: A randomised crossover trial. Issue 12 (December 2018)

• Record Type: Journal Article
• Authors: Maylor, Benjamin D.; Zakrzewski-Fruer, Julia K.; Orton, Charlie J.; Bailey, Daniel P.
• Is Part Of: Journal of science and medicine in sport. Volume 21:Issue 12(2018)
• Page Start: 1250
• Page End: 1255
• Publication Date: 2018-12
• Subjects: CI confidence interval -- CVD cardiovascular disease -- HDL-C high-density lipoprotein cholesterol -- iAUC incremental area under the curve -- MVPA moderate-to-vigorous physical activity -- PA physical activity -- RPE rating of perceived exertion -- tAUC total area under the curve; Sedentary behaviour -- Postprandial metabolism -- Prolonged sitting -- Cardiometabolic disease -- Physical activity; Sports sciences -- Periodicals; Sports medicine -- Periodicals; Exercise -- Physiological aspects -- Periodicals; Sports -- physiology -- Periodicals; Sports Medicine -- Periodicals; Sportgeneeskunde; 617.102705
• DOI: 10.1016/j.jsams.2018.05.022
• Languages: English
• ISSNs: 1440-2440

Abstract

Abstract: Objectives: To compare the postprandial cardiometabolic response to prolonged sitting, continuous moderate-intensity physical activity (PA) followed by prolonged sitting, and interrupting prolonged sitting with hourly high-intensity PA breaks. Design: Three-condition randomised crossover trial. Methods: Fourteen sedentary and inactive adults aged 29 ± 9 years took part in three, 8-h conditions: (1) prolonged sitting (SIT), (2) a continuous 30-min moderate-intensity PA bout followed by prolonged sitting (CONT-SIT), and (3) sitting interrupted hourly with 2 min 32 s high-intensity PA bouts (SIT-ACT). The treadmill PA in conditions 2 and 3 were matched for energy expenditure. Two standardised test meals were consumed during each condition. Incremental area under the curve (iAUC) for each 8-h condition was calculated for glucose, insulin, triglyceride, and high-density lipoprotein cholesterol (HDL-C) concentrations. Statistical analyses were completed using linear mixed models. Results: Compared with SIT, SIT-ACT lowered triglyceride iAUC by 2.23 mmol/L ∙ 8 h (95% CI −4.33, −0.13) and raised HDL-C iAUC by 0.99 mmol/L ∙ 8 h (0.05, 1.93) (all p ≤ 0.038). There was no significant difference in triglyceride or HDL-C iAUC between CONT-SIT and SIT or SIT-ACT (p ≥ 0.211). There were no significant differences between conditions for glucose or insulin iAUC (p ≥ 0.504). Conclusions: This study suggests that interrupting prolonged sitting with hourly high-intensity PA breaks acutely improves postprandial triglyceride and HDL-C concentrations compared with prolonged sitting, whereas a continuous moderate-intensity PA bout does not.