Biomedical Applications: Tunable Delivery of siRNA from a Biodegradable Scaffold to Promote Angiogenesis In Vivo (Adv. Mater. 4/2014). (23rd January 2014) - Nelson, Christopher E.
Abstract : On page 607, C. L. Duvall and co‐workers detail a new technology for sustained, local delivery of siRNA. The authors apply this platform to manipulate activity of a pro‐angiogenic transcription factor, which orchestrates robust biomaterial scaffold neovascularization in vivo. This system may provide a superior approach to traditional pro‐angiogenic therapies and holds promise for broader application in regenerative medicine.