Re-investigating PLK1 inhibitors as antimitotic agents. (2nd November 2017)
- Record Type:
- Journal Article
- Title:
- Re-investigating PLK1 inhibitors as antimitotic agents. (2nd November 2017)
- Main Title:
- Re-investigating PLK1 inhibitors as antimitotic agents
- Authors:
- Delacour, Quentin
Gavet, Olivier - Abstract:
- ABSTRACT: Polo-like kinase 1 (PLK1) plays key roles during mitosis, prompting the development of PLK1 inhibitors for anticancer therapy. We recently determined that PLK1 is crucially required for entry into mitosis. Hence, we discuss the potential and limitations of PLK1 inhibition strategies to promote mitotic arrest and death of cancer cells.
- Is Part Of:
- Molecular & cellular oncology. Volume 4:Number 6(2017)
- Journal:
- Molecular & cellular oncology
- Issue:
- Volume 4:Number 6(2017)
- Issue Display:
- Volume 4, Issue 6 (2017)
- Year:
- 2017
- Volume:
- 4
- Issue:
- 6
- Issue Sort Value:
- 2017-0004-0006-0000
- Page Start:
- Page End:
- Publication Date:
- 2017-11-02
- Subjects:
- Polo-like kinase 1 -- kinase inhibitor -- antimitotic -- G2 phase -- cancer
Tumors -- Periodicals
Neoplasms
Periodicals
616.99 - Journal URLs:
- http://www.tandfonline.com/loi/kmco20#.VyIIeFL2aic ↗
http://www.tandfonline.com/ ↗ - DOI:
- 10.1080/23723556.2017.1356430 ↗
- Languages:
- English
- ISSNs:
- 2372-3556
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 8578.xml