Cisplatin resistance coupled to enhanced sensitivity to metabolic interventions. (2nd November 2018)
- Record Type:
- Journal Article
- Title:
- Cisplatin resistance coupled to enhanced sensitivity to metabolic interventions. (2nd November 2018)
- Main Title:
- Cisplatin resistance coupled to enhanced sensitivity to metabolic interventions
- Authors:
- Castedo, Maria
Obrist, Florine
Kroemer, Guido - Abstract:
- ABSTRACT: Specific metabolic alterations have recently been observed in cisplatin-resistant cancers. As a result, cisplatin resistance can be overcome by co-administration of pyridoxine, and cisplatin-resistant cancer cells become exquisitely sensitive to killing by inhibitors of poly(ADP-ribose) polymerase, starvation, and antimetabolites targeting nucleotide biosynthesis.
- Is Part Of:
- Molecular & cellular oncology. Volume 5:Number 6(2018)
- Journal:
- Molecular & cellular oncology
- Issue:
- Volume 5:Number 6(2018)
- Issue Display:
- Volume 5, Issue 6 (2018)
- Year:
- 2018
- Volume:
- 5
- Issue:
- 6
- Issue Sort Value:
- 2018-0005-0006-0000
- Page Start:
- Page End:
- Publication Date:
- 2018-11-02
- Subjects:
- chemotherapy -- DNA damage response -- non-small cell lung cancer
Tumors -- Periodicals
Neoplasms
Periodicals
616.99 - Journal URLs:
- http://www.tandfonline.com/loi/kmco20#.VyIIeFL2aic ↗
http://www.tandfonline.com/ ↗ - DOI:
- 10.1080/23723556.2018.1526004 ↗
- Languages:
- English
- ISSNs:
- 2372-3556
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 8548.xml