Sequential experimentation for mixtures. (1st January 2012)

• Record Type: Journal Article
• Authors: Weese, Maria L.; Leitnaker, Mary G.
• Is Part Of: International journal of experimental design and process optimisation. Volume 3:Number 1(2012)
• Page Start: 33
• Page End: 42
• Publication Date: 2012-01-01
• Subjects: Cox mixture model -- mixture experiments -- mixture process optimisation -- model independence -- sequential experimentation; Experimental design -- Periodicals; Process control -- Statistical methods -- Periodicals; 620.0072
• Languages: English
• ISSNs: 2040-2252

Abstract

We present a sequential method for experimenting with mixtures when the number of mixture components is large and the experimental goal is to gain information on a subset of components for the purpose of mixture product improvement. The model-independent method utilises parameter estimates from the Cox mixture model with a current product formulation from which to begin experimentation. The advantages of our method are the ability to perform experiments using a split-plot like structure and utilise it in a sequential manner on an operating process.