Performance assessments of vertically aligned carbon nanotubes multi-electrode arrays using Cath.a-differentiated (CAD) cells. (29th July 2015)

• Record Type: Journal Article
• Authors: Jeong, Du Won; Jung, Jongjin; Hwa Kim, Gook; Yang, Cheol-Soo; Jin Kim, Ju; Don Jung, Sang; Lee, Jeong-O
• Is Part Of: Nanotechnology. Volume 26:Number 33(2015)
• Publication Date: 2015-07-29
• Subjects: vertically aligned carbon nanotubes -- graphene -- multielectrode arrays -- CAD cell; Nanotechnology -- Periodicals; Nanotechnology -- Periodicals; Nanotechnology; Publications périodiques; Nanotechnologies; Periodicals; 620.5
• DOI: 10.1088/0957-4484/26/33/335701
• Languages: English
• ISSNs: 0957-4484

Abstract

Abstract: In this work, Cath.a-differentiated (CAD) cells were used in place of primary neuronal cells to assess the performance of vertically aligned carbon nanotubes (VACNTs) multi-electrode arrays (MEA). To fabricate high-performance MEA, VACNTs were directly grown on graphene/Pt electrodes via plasma enhanced chemical deposition technique. Here, graphene served as an intermediate layer lowering contact resistance between VACNTs and Pt electrode. In order to lower the electrode impedance and to enhance the cell adhesion, VACNTs-MEAs were treated with UV–ozone for 20 min. Impedance of VACNTs electrode at 1 kHz frequency exhibits a reasonable value (110 k Ω ) for extracellular signal recording, and the signal to noise ratio the is good enough to measure low signal amplitude (15.7). Spontaneous firing events from CAD cells were successfully measured with VACNTs MEAs that were also found to be surprisingly robust toward the biological interactions.