Zanthoxylum armatum DC.: Current knowledge, gaps and opportunities in Nepal. (30th January 2019)

• Record Type: Journal Article
• Authors: Phuyal, Nirmala; Jha, Pramod Kumar; Prasad Raturi, Pankaj; Rajbhandary, Sangeeta
• Is Part Of: Journal of ethnopharmacology. Volume 229(2018)
• Page Start: 326
• Page End: 341
• Publication Date: 2019-01-30
• Subjects: KATH National Herbarium -- TUCH Tribhuvan University Central Herbarium -- GC-MS Gas chromatography-mass spectrometry -- MIC Minimal inhibitory concentration -- DPPH 2, 2-Diphenyl-1-picrylhydrazyl -- SOD Superoxide dismutase -- CAT Catalase -- GSH Glutathione -- CCl4 Carbon tetrachloride, SGOT, serum glutamyl oxalacetic acid transaminase -- SGPT serum glutamyl pyruvate transaminases -- ALKP alkaline phosphatase -- SBLN serum bilirubin -- ALT Alanine aminotransferase -- AST aspartate aminotransferase -- ALP alkaline phosphatase -- DBil direct bilirubin -- TBil. Total bilirubin, DEET diethyl-3methylbenzamide, NRs Nepali Rupees -- MAPs medicinal and aromatic plants -- NTFPs non-timber forest products -- WHO World Health Organization -- ISO The International Organization for Standardization; Linalool (CID: 6549) -- Limonene (CID: 440917) -- α-Phellandrene (CID: 7460) -- β –Phellandrene (CID: 11142) -- Myrcene (CID: 31253) -- P-Cymene (CID: 7463) -- Camphene (CID: 6616) -- β-Amyrin (CID: 73145) -- Vitexin (CID: 5280441) -- Tambulin (CID: 5281700) -- Berberine (CID: 2353) -- G-Fagarine (CID: 107936) -- B-Fagarine (CID: 637520) -- Asarinin (CID: 233333) -- Sesamin (CID: 72307) -- Bergapten (CID: 2355) -- Xanthyletin (CID: 65188) -- Methyl cinnamate (CID: 637520) -- Armatamide (CID: 5320157) -- β-Sitosterol-β-D-Glucoside (CID: 91884650); Zanthoxylum armatum -- Timur -- Phytochemistry -- Pharmacology -- Biological activities; Ethnopharmacology -- Periodicals; Pharmacognosy -- Periodicals; Herbs -- Periodicals; Herbs -- Periodicals; Pharmacognosy -- Periodicals; Pharmacognosie -- Périodiques; Herbes -- Périodiques; 615.1
• DOI: 10.1016/j.jep.2018.08.010
• Languages: English
• ISSNs: 0378-8741

Abstract

Abstract: Ethnopharmacological relevance: Zanthoxylum armatum DC. possesses several medicinal properties and has been commonly used in different indigenous medicinal practices to cure several diseases because of its stomachic, carminative and anthelmintic properties. Aim: This review paper aims to provide an update on and analysis of information about the ecology, uses, phytochemistry, pharmacology, trade opportunities, policy gaps for the commercialization of this species forming a basis for further scientific innovations Materials and methods: Information was gathered through a search of different books, journals, articles, annual reports, proceedings and web-based materials. Result: Alkaloids, sterols, phenolics, lignins coumarins, terpenoids and flavonoids have been identified from leaves, fruits, stem, bark and seeds. Its trade value is also very high with its manifold applications in Ayurveda, allopathy, general pharmacy, and other industries. Antimicrobial, antiviral, antioxidant, anti-inflammatory, cytotoxic, hepato-protective, insecticidal/larvicidal effects are of particular relevance. Conclusion: It is one of the prioritized medicinal plants for economic development in Nepal. Owing to its diverse applications, the species can be developed as an important commodity for alleviation of poverty in rural areas. The various ethno-pharmacological applications of Zanthoxylum armatum have been verified by several related researches. More extensive study on the individual specific phyto-component can lead to novel innovations for the well-being of mankind. Graphical abstract: