Water versus DNA A new deal for proton transport modeling in biological matter. (July 2015)

• Record Type: Journal Article
• Authors: Champion, C; Quinto, M A; Monti, J M; Galassi, M E; Week, P F; Fojón, O A; Hanssen, J; Rivarola, R D
• Is Part Of: Journal of physics. Number 635(2015)
• Publication Date: 2015-07
• Subjects: Physics -- Congresses; 530.5
• DOI: 10.1088/1742-6596/635/3/032064
• Languages: English
• ISSNs: 1742-6588

Abstract

Synopsis: Water vapor is a common surrogate of DNA for modeling the proton-induced ionizing processes in living tissue exposed to radiations. The present study aims at scrutinizing the validity of this approximation and then revealing new insights into proton-induced energy transfers by a comparative analysis between water and realistic biological medium. In this context, self-consistent quantum mechanical modeling of the ionization and electron capture processes is reported within the continuum distorted wave-eikonal initial state framework for both isolated water molecules and DNA components impacted by proton beams.