Theranostic Nanoparticles for Tracking and Monitoring Disease State. (June 2018)

• Record Type: Journal Article
• Authors: Zavaleta, Cristina; Ho, Dean; Chung, Eun Ji
• Other Names: Jeyasekharan Anand D. guest-editor.
• Is Part Of: SLAS technology. Volume 23:Number 3(2018)
• Page Start: 281
• Page End: 293
• Publication Date: 2018-06
• Subjects: nanotechnology -- characterization -- fabrication -- nanobiotech; Medical laboratory technology -- Periodicals; Laboratories -- Equipment and supplies -- Periodicals; Diagnosis, Laboratory -- Periodicals; 616.075
• DOI: 10.1177/2472630317738699
• Languages: English
• ISSNs: 2472-6303

Abstract

The development of novel nanoparticles consisting of both diagnostic and therapeutic components has increased over the past decade. These "theranostic" nanoparticles have been tailored toward one or more types of imaging modalities and have been developed for optical imaging, magnetic resonance imaging, ultrasound, computed tomography, and nuclear imaging comprising both single-photon computed tomography and positron emission tomography. In this review, we focus on state-of-the-art theranostic nanoparticles that are capable of both delivering therapy and self-reporting/tracking disease through imaging. We discuss challenges and the opportunity to rapidly adjust treatment for individualized medicine.