A Perylene diimide based fluorescent probe for caffeine in aqueous medium. Issue 1 (2nd January 2019)

• Record Type: Journal Article
• Authors: Karmakar, Parthasarathi; Manna, Srimanta; Maiti, Kalipada; Ali, Syed Samim; Guria, Uday Narayan; Sarkar, Ripon; Datta, Pallab; Mandal, Debasish; Mahapatra, Ajit Kumar
• Is Part Of: Supramolecular chemistry. Volume 31:Issue 1(2019)
• Page Start: 28
• Page End: 35
• Publication Date: 2019-01-02
• Subjects: Aspartic acid modified perylene diimide -- caffeine sensing -- fluorescent probe -- π-π interaction -- density functional theory calculations -- cell imaging study; Macromolecules -- Periodicals; Supramolecular chemistry -- Periodicals; 547.005
• DOI: 10.1080/10610278.2018.1530352
• Languages: English
• ISSNs: 1061-0278

Abstract

ABSTRACT: Caffeine is a legal stimulant drug which has received considerable attention due to its widespread use as a beverage and in pharmaceutical formulations. However, reported chemosensors for caffeine are limited. In the present study use of a perylene diimide (PDI) derivative has been explored for the first time for detection and quantification of caffeine in an aqueous medium. Spectroscopic studies (UV-Vis, Fluorescence, FTIR and 1H-NMR) suggest that aspartic acid modified perylene diimide (PASP ) may bind to caffeine through π-π interaction. This interaction results in immediate quenching of fluorescence and optical color change which can be perceived through naked eyes. This probe has been successfully used for bio-imaging of caffeine in living cells. Graphical Abstract: