Antifungal, antibacterial, antibiofilm and colorimetric sensing of toxic metals activities of eco friendly, economical synthesized Ag/AgCl nanoparticles using Malva Sylvestris leaf extracts. (December 2018)

• Record Type: Journal Article
• Authors: Feizi, Sholeh; Taghipour, Elham; Ghadam, Parinaz; Mohammadi, Parisa
• Is Part Of: Microbial pathogenesis. Volume 125(2018)
• Page Start: 33
• Page End: 42
• Publication Date: 2018-12
• Subjects: Malva Sylvestris -- Ag/AgCl nanoparticles -- Anti fungal -- Antibacterial -- Anti biofilm -- Toxic metals detection; Pathogenic microorganisms -- Periodicals; Pathology, Molecular -- Periodicals; Communicable Diseases -- microbiology -- Periodicals; Communicable Diseases -- parasitology -- Periodicals; Micro-organismes pathogènes -- Périodiques; Pathologie moléculaire -- Périodiques; Electronic journals; 616.9041
• DOI: 10.1016/j.micpath.2018.08.054
• Languages: English
• ISSNs: 0882-4010

Abstract

Abstract: Silver nanoparticles, one of the most popular nanomaterials, are used extensively in medicine and industries. The present study biosynthesized spherical Ag/AgCl nanoparticles with a size range of 10–50 nm in less than 5 min. The synthesis was performed in a single step, in a low-cost and eco-friendly manner, from the aqueous extract of Malva Sylvestris leaves. The aqueous extract had a large number of phenolic compounds and carbohydrates as reducing and capping agents. The nanoparticles also showed significant antibacterial and anti-biofilm activities against some multi drug resistant bacteria. They additionally showed antifungal activities on several Candida species. The highest concentration of Ag/AgCl-NPs (62.5 μg/ml) was required in order to inhibit P. aeruginosa B 52, C. glabrata and C. parapsilosis growth. The lowest concentration of Ag/AgCl-NPs (7.8125 μg/ml) inhibited the growth of C. orthopsilosis, P. aeruginosa ATCC 27853 and B. subtilis ATCC 6633 . A total of 125 μg/ml of Ag/AgCl-NPs was used to prevent P. aeruginosa B 52 biofilm growth. The concentration of 62.5 μg/ml Ag/AgCl-NPs also eradicated both P. aeruginosa 48 and P. aeruginosa B 52 biofilms. The results showed that Hg 2+ and Pb 2+ contaminants in water could be colorimetrically detected by these nanoparticles. Graphical abstract: