Right ventricular outflow tract obstruction: a quest for ideal management. (July 2018)

• Record Type: Journal Article
• Authors: Murala, John SK; Vela, Ryan J; Geoffrion, Tracy; Chopra, Surpreet; Guhathakurtha, Soma; Pezzella, Thomas; Cherian, Kotturathu Mammen
• Is Part Of: Asian cardiovascular & thoracic annals. Volume 26:Number 6(2018)
• Page Start: 451
• Page End: 460
• Publication Date: 2018-07
• Subjects: Heart defects -- congenital -- Prosthesis design -- Pulmonary valve -- Transplantation -- autologous Transplantation -- homologous -- Ventricular outflow obstruction; Heart -- Diseases -- Asia -- Periodicals; Heart -- Diseases -- Pacific Area -- Periodicals; Heart -- Diseases -- Periodicals; Heart -- Surgery -- Asia -- Periodicals; Heart -- Surgery -- Pacific Area -- Periodicals; Heart -- Surgery -- Periodicals; Chest -- Surgery -- Asia -- Periodicals; Chest -- Surgery -- Pacific Area -- Periodicals; Chest -- Surgery -- Periodicals; 617.412
• DOI: 10.1177/0218492318779963
• Languages: English
• ISSNs: 0218-4923

Abstract

Management of right ventricular outflow tract obstruction has undergone much change over the last century. Techniques described in the literature include anatomical repairs and the use of various patches, conduits, and innovative grafts. However, many of these approaches require reoperations or catheter-based interventions, leading to increased morbidity, mortality, and cost. The search for the ideal long-lasting conduit continues and there are new techniques on the horizon, using genetic engineering and nanotechnology. This review discusses the evolution of various techniques for repair of right ventricular outflow tract obstruction, past and current conduits, as well as ongoing research.