Copper-catalyzed decarboxylative and oxidative decarbonylative cross-coupling between cinnamic acids and aliphatic aldehydes. Issue 22 (12th October 2018)

• Record Type: Journal Article
• Authors: Luo, Zaigang; Han, Xinxin; Fang, Yuyu; Liu, Peng; Feng, Chengtao; Li, Zhong; Xu, Xuemei
• Is Part Of: Organic chemistry frontiers. Volume 5:Issue 22(2018)
• Page Start: 3299
• Page End: 3305
• Publication Date: 2018-10-12
• Subjects: Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1039/c8qo00927a
• Languages: English
• ISSNs: 2052-4110

Abstract

Abstract : A convenient copper-catalyzed decarboxylative and oxidative decarbonylative cross-coupling of cinnamic acids with aliphatic aldehydes was achieved, which provides a useful strategy of C(sp 3 )–C(sp 2 ) bonds construction for the synthesis of alkyl-substituted E -alkenes. Abstract : A copper-catalyzed decarboxylative and oxidative decarbonylative cross-coupling of cinnamic acids with aliphatic aldehydes was achieved. The reaction undergoes subsequent decarbonylation, radical addition and decarboxylation processes with aliphatic aldehydes as the cheap and abundant alkyl radical source. This procedure offers a complementary approach to the convenient generation of alkyl-substituted E -alkenes.