The first 9 years of kidney paired donation through the National Kidney Registry: Characteristics of donors and recipients compared with National Live Donor Transplant Registries. Issue 11 (30th April 2018)

• Record Type: Journal Article
• Authors: Flechner, Stuart M.; Thomas, Alvin G.; Ronin, Matthew; Veale, Jeffrey L.; Leeser, David B.; Kapur, Sandip; Peipert, John D.; Segev, Dorry L.; Henderson, Macey L.; Shaffer, Ashton A.; Cooper, Matthew; Hil, Garet; Waterman, Amy D.
• Is Part Of: American journal of transplantation. Volume 18:Issue 11(2018)
• Page Start: 2730
• Page End: 2738
• Publication Date: 2018-04-30
• Subjects: clinical research/practice -- donors and donation: living -- donors and donation: paired exchange -- kidney transplantation/nephrology; Transplantation of organs, tissues, etc -- Periodicals; 617.95
• DOI: 10.1111/ajt.14744
• Languages: English
• ISSNs: 1600-6135

Abstract

Abstract : The practice of kidney paired donation (KPD) is expanding annually, offering the opportunity for live donor kidney transplant to more patients. We sought to identify if voluntary KPD networks such as the National Kidney Registry (NKR) were selecting or attracting a narrower group of donors or recipients compared with national registries. For this purpose, we merged data from the NKR database with the Scientific Registry of Transplant Recipients (SRTR) database, from February 14, 2008, to February 14, 2017, encompassing the first 9 years of the NKR. Compared with all United Network for Organ Sharing (UNOS) live donor transplant patients (49 610), all UNOS living unrelated transplant patients (23 319), and all other KPD transplant patients (4236), the demographic and clinical characteristics of NKR transplant patients (2037) appear similar to contemporary national trends. In particular, among the NKR patients, there were a significantly ( P < .001) greater number of retransplants (25.6% vs 11.5%), hyperimmunized recipients (22.7% vs 4.3% were cPRA >80%), female recipients (45.9% vs 37.6%), black recipients (18.2% vs 13%), and those on public insurance (49.7% vs 41.8%) compared with controls. These results support the need for greater sharing and larger pool sizes, perhaps enhanced by the entry of compatible pairs and even chains initiated by deceased donors, to unlock more opportunities for those harder‐to‐match pairs. Abstract : Favorable demographic characteristics are reported for both donors and recipients transplanted during the first 9 years of the National Kidney Registry.