Cu(i)/{Nb6O19} catalyzed N-acylation of arylacetic acids with amines under aerobic conditions. Issue 88 (19th October 2018)

• Record Type: Journal Article
• Authors: Li, Pei-He; Wang, Zheng; Fu, Hui; Dai, Qi-Pu; Hu, Chang-Wen
• Is Part Of: Chemical communications. Volume 54:Issue 88(2018)
• Page Start: 12471
• Page End: 12474
• Publication Date: 2018-10-19
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c8cc06721j
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : Employing a simple copper(i )/{Nb6 O19 } catalyst system, the reaction reported herein offers a facile process to give functionalized α-ketoamides from readily available arylacetic acids under aerobic conditions. Abstract : The method described herein is a general, efficient and green approach to synthesize α-ketoamides from arylacetic acids and amines. Employing a simple copper(i )/{Nb6 O19 } catalyst system, the reaction offers a facile process to give functionalized α-ketoamides from readily available arylacetic acids under aerobic conditions. The merit of this new strategy is that it expands the syntheses of α-ketoamides from stable, inexpensive and widely available acylation reagents such as arylacetic acids in one step.