Plasmacytoid myoepithelioma: Diagnostic algorithm and a tailored therapeutic protocol for a geriatric individual. Issue 5 (September 2015)

• Record Type: Journal Article
• Authors: Patel, Pratik N.; Thennavan, Aatish; Narayanaswamy, Venkadasalapathy; Radhakrishnan, Raghu
• Is Part Of: Journal of oral and maxillofacial surgery, medicine, and pathology. Volume 27:Issue 5(2015)
• Page Start: 737
• Page End: 740
• Publication Date: 2015-09
• Subjects: Plasmacytoid myoepithelioma -- Geriatric patient -- Facial translocation -- Cytokeratin (CK) -- Glial fibrillar acidic protein (GFAP); Mouth -- Surgery -- Periodicals; Face -- Surgery -- Periodicals; Maxilla -- Surgery -- Periodicals; Oral medicine -- Periodicals; Mouth -- Diseases -- Pathogenesis -- Periodicals; Surgery, Oral -- Periodicals; Oral Medicine -- Periodicals; Pathology, Oral -- Periodicals; Face -- Surgery; Maxilla -- Surgery; Mouth -- Diseases -- Pathogenesis; Mouth -- Surgery; Oral medicine; Electronic journals -- Sciences; Electronic journals -- Medicine; Periodicals; 617.522059
• DOI: 10.1016/j.ajoms.2015.01.007
• Languages: English
• ISSNs: 2212-5566

Abstract

Abstract: Plasmacytoid myoepithelioma (PM) is an exceedingly rare tumour, which often arises in the minor salivary glands. An 81-year-old male presenting with a massive growth occupying the entire palatal vault was operated by facial translocation approach. Histologically, a well-encapsulated tumour composed of numerous plasmacytoid myoepithelial cells arranged in an organoid pattern could be elicited. Diffuse immunoreactivity to pan-cytokeratin and glial fibrillar acidic protein pointed to a myoepithelial origin of the tumour, and low labelling index of Ki-67 indicated its benign nature. A conservative surgical procedure bearing in mind the age of the patient and ruling out other closely mimicking salivary gland tumours by immunohistochemistry highlights the importance of a tailored surgicopathological approach in geriatric patients to reduce post-operative morbidity.