A practical total synthesis of (±)-cermizine D and a formal synthesis of (±)-cermizine C. (1st June 2018)
- Record Type:
- Journal Article
- Title:
- A practical total synthesis of (±)-cermizine D and a formal synthesis of (±)-cermizine C. (1st June 2018)
- Main Title:
- A practical total synthesis of (±)-cermizine D and a formal synthesis of (±)-cermizine C
- Authors:
- Shi, Xin
Bao, Ying
Deng, Zhen-Tao
Zhu, Yu
Shao, Li-Dong
Zhang, Hong-Bin
Zhao, Qin-Shi - Abstract:
- A practical total synthesis of (±)-cermizine D and a formal synthesis of (±)-cermizine C were achieved. The four-step total synthesis comprised mainly a Michael addition, a Weinreb amide-activated substitution and a sequence of ketalation/PtO2-catalysed dearomatisation/reductive amination reactions that resulted in ring closure in 13.7% overall yield. The formal synthesis was accomplished in 29.7% overall yield.
- Is Part Of:
- Journal of chemical research. Volume 42:Number 5(2018)
- Journal:
- Journal of chemical research
- Issue:
- Volume 42:Number 5(2018)
- Issue Display:
- Volume 42, Issue 5 (2018)
- Year:
- 2018
- Volume:
- 42
- Issue:
- 5
- Issue Sort Value:
- 2018-0042-0005-0000
- Page Start:
- 274
- Page End:
- 279
- Publication Date:
- 2018-06-01
- Subjects:
- Chemistry -- Research -- Periodicals
Chemistry -- Periodicals
540.5 - Journal URLs:
- http://stl.publisher.ingentaconnect.com/content/stl/jcr ↗
https://journals.sagepub.com/home/chl ↗
http://www.sciencereviews2000.co.uk/ ↗ - DOI:
- 10.3184/174751918X15271572210923 ↗
- Languages:
- English
- ISSNs:
- 1747-5198
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 8399.xml