IGRA-Based Screening for Latent Tuberculosis Infection in Persons Newly Incarcerated in New York City Jails. (April 2018)

• Record Type: Journal Article
• Authors: Katyal, Monica; Leibowitz, Ruth; Venters, Homer
• Is Part Of: Journal of correctional health care. Volume 24:Number 2(2018)
• Page Start: 156
• Page End: 170
• Publication Date: 2018-04
• Subjects: tuberculosis -- latent tuberculosis infection -- tuberculin skin test -- interferon gamma release assay -- correctional health; Prisoners -- Health and hygiene -- United States -- Periodicals; Prisoners -- Medical care -- United States -- Periodicals; 365.667
• DOI: 10.1177/1078345818763868
• Languages: English
• ISSNs: 1078-3458

Abstract

In the United States, latent tuberculosis infection (LTBI) detection in correctional settings is a public health priority. Interferon gamma release assay (IGRA)-based LTBI screening was introduced in New York City jails in 2011 to 2012, replacing historically used tuberculin skin testing (TST), which was associated with substantial incomplete screening rates. This retrospective, cross-sectional study evaluated LTBI screening outcomes and correlates of positivity in 40, 986 persons newly incarcerated in 2011 to 2013. Of 35, 090 eligible patients tested (96.4%), final results were 6.3% positive, 93.4% negative, and 0.2% indeterminate. In multivariable regression modeling, sex, age, race/ethnicity, nativity, marital status, prior jail incarceration, and HIV status were correlated with positivity. IGRA-based screening yielded high screening and low indeterminate test rates and may be recommended in correctional and other settings where TST is currently used.