Effectiveness of Single- and Multiple-Tablet Antiretroviral Regimens in Correctional Setting for Treatment-Experienced HIV Patients. (January 2018)

• Record Type: Journal Article
• Authors: Merker, Andrew; Badowski, Melissa; Chiampas, Thomas; Pérez, Sarah E.; Patel, Mahesh; Young, Jeremy; Werner, Ryan
• Is Part Of: Journal of correctional health care. Volume 24:Number 1(2018)
• Page Start: 52
• Page End: 61
• Publication Date: 2018-01
• Subjects: HIV -- department of corrections -- antiretroviral regimens -- correctional health care; Prisoners -- Health and hygiene -- United States -- Periodicals; Prisoners -- Medical care -- United States -- Periodicals; 365.667
• DOI: 10.1177/1078345817745334
• Languages: English
• ISSNs: 1078-3458

Abstract

Minimal information is available regarding antiretroviral prescribing patterns and outcomes for HIV patients in correctional systems. This study analyzes single- (STR) and multiple- (MTR) tablet regimen effectiveness in patients receiving HIV telemedicine care through the Illinois Department of Corrections (IDOC). This study involves a retrospective review of HIV-positive adult patients in IDOC on either an STR (efavirenz, rilpivirine, elvitegravir based) or an MTR (emtricitabine/tenofovir with atazanavir/ritonavir, darunavir/ritonavir, or raltegravir). No significant differences in virologic suppression were seen between groups at baseline, weeks 24, 48, 96, and last clinic visit. Similar proportions of patient-reported adverse effects, self-reported adherence, and discontinuation rates were found in both groups. With similar rates of viral suppression, tolerability, adherence, and discontinuation, administering MTR in the incarcerated population is a viable alternative to STR.