Prospects for the research and application of biodegradable ureteral stents: from bench to bedside. Issue 14 (22nd September 2018)

• Record Type: Journal Article
• Authors: Wang, Lin; Yang, Ganggang; Xie, Hua; Chen, Fang
• Is Part Of: Journal of biomaterials science. Volume 29:Issue 14(2018)
• Page Start: 1657
• Page End: 1666
• Publication Date: 2018-09-22
• Subjects: Stent -- ureteral stent -- biodegradable -- biomaterial -- design; Polymers -- Biocompatibility -- Periodicals; Biomedical materials -- Periodicals; 572.33
• DOI: 10.1080/09205063.2018.1498184
• Languages: English
• ISSNs: 0920-5063

Abstract

Abstract: Ureteral stents are commonly used in urological practices but are frequently associated with patient discomfort, encrustation and stent-related infection. And a second procedure is needed to remove the stent. New biomaterials and designs have been attempted to solve these problems. The development of biodegradable ureteral stent shows promising prospects in future clinical applications. This article reviews the biomaterials and preparation methods commonly used in the present study of biodegradable ureteral stents. To date, none of the technological developments has lead to the 'ideal' biodegradable ureteral stent, but much progress has been made in the stent design by improving the physical characteristics and biocompatibility of the biomaterials. The controllability of degradation, the biggest problem faced currently, still needs to be further improved. In the future, the nanotechnology and chemical modification of biomaterials may be able to further optimize the properties of degradation.