Reality of obesity paradox: Results of percutaneous coronary intervention in Middle Eastern patients. Issue 4 (April 2018)

• Record Type: Journal Article
• Authors: Jarrah, Mohamad; Hammoudeh, Ayman J.; Khader, Yousef; Tabbalat, Ramzi; Al-Mousa, Eyas; Okkeh, Osama; Alhaddad, Imad A.; Tawalbeh, Loai Issa; Hweidi, Issa M.
• Is Part Of: Journal of international medical research. Volume 46:Issue 4(2018)
• Page Start: 1595
• Page End: 1605
• Publication Date: 2018-04
• Subjects: Cardiovascular disease -- obesity -- obesity paradox -- Middle Eastern patients -- percutaneous coronary intervention -- major adverse cardiovascular events; Medicine -- Periodicals; Pharmacology -- Periodicals; 610.5
• DOI: 10.1177/0300060518757354
• Languages: English
• ISSNs: 0300-0605

Abstract

Objective: The aim of this study was to assess the baseline clinical characteristics, coronary angiographic features, and adverse cardiovascular events during hospitalization and at 1 year of follow-up in obese patients compared with overweight and normal/underweight patients. Methods: A prospective, multicenter study of consecutive patients undergoing percutaneous coronary intervention was performed. Results: Of 2425 enrolled patients, 699 (28.8%) were obese, 1178 (48.6%) were overweight, and 548 (22.6%) were normal/underweight. Obese patients were more likely to be female and to have a higher prevalence of diabetes, hypertension, hypercholesterolemia, or previous percutaneous coronary intervention. Acute coronary syndrome was the indication for percutaneous coronary intervention in 77.0% of obese, 76.4% of overweight, and 77.4% of normal/underweight patients. No significant differences in the prevalence of multi-vessel coronary artery disease or multi-vessel percutaneous coronary intervention were found among the three groups. Additionally, no significant differences were found in stent thrombosis, readmission bleeding rates, or cardiac mortality among the three groups during hospitalization, at 1 month, and at 1 year. Conclusion: The major adverse cardiovascular event rate was the same among the three groups throughout the study period. Accordingly, body mass index is considered a weak risk factor for cardiovascular comorbidities in Arab Jordanian patients.