Neurologic Injury With Severe Adult Respiratory Distress Syndrome in Patients Undergoing Extracorporeal Membrane Oxygenation: A Single-Center Retrospective Analysis. (November 2017)

• Record Type: Journal Article
• Authors: Klinzing, Stephanie; Wenger, Urs; Stretti, Federica; Steiger, Peter; Rushing, Elisabeth J.; Schwarz, Urs; Maggiorini, Marco
• Is Part Of: Anesthesia & analgesia. Volume 125:Number 5(2017)
• Publication Date: 2017-11
• Subjects: Anesthesiology -- Periodicals; Anesthesia; Anesthesiology; Analgesia; Analgesics; Anesthesiology -- Periodicals; 617.9605
• DOI: 10.1213/ANE.0000000000002431
• Languages: English
• ISSNs: 0003-2999

Abstract

Abstract : This retrospective single-center study investigated the incidence of neurologic injury as determined by autopsy or cerebral imaging in 74 patients undergoing extracorporeal membrane oxygenation (ECMO) for acute respiratory distress syndrome. Seventy-three percent of patients were treated with venovenous and 27% with venoarterial ECMO. ECMO-associated intracerebral hemorrhage was diagnosed in 10.8% of patients. There were no cases of ischemic stroke. Clinical characteristics did not differ between patients with and without neurologic injury. Six-month survival was 13% (Wilson confidence interval, 2%–47%) in patients with severe intracerebral hemorrhage compared to an overall survival rate of 57% (Wilson confidence interval, 45%–67%). Abstract : Published ahead of print August 31, 2017.