Statistical evaluation of NMR backbone resonance assignment. (10th May 2006)

• Record Type: Journal Article
• Authors: Lin, Guohui; Wan, Xiang; Tegos, Theodore; Li, Yingshu
• Is Part Of: International journal of bioinformatics research and applications. Volume 2:Number 2(2006)
• Page Start: 147
• Page End: 160
• Publication Date: 2006-05-10
• Subjects: protein structure determination -- NMR sequential resonance assignment -- statistical evaluation -- normal distribution -- bioinformatics -- simulation -- nuclear magnetic resonance spectroscopy; Bioinformatics -- Periodicals; 570.285
• Languages: English
• ISSNs: 1744-5485

Abstract

This paper proposes a novel statistical evaluation model for automated protein NMR sequential resonance assignment. It can be bound to any assignment program and provides confidences for the whole output assignment and each individual mapping. A simulation study on a set of four proteins shows that the statistical evaluation results are informative.