Cosmetic Talc–Related Pulmonary Granulomatosis. (September 2017)

• Record Type: Journal Article
• Authors: Jasuja, Sonia; Kuhn, Brooks T.; Schivo, Michael; Adams, Jason Y.
• Is Part Of: Journal of investigative medicine high impact case reports. Volume 5:Number 3(2017)
• Publication Date: 2017-09
• Subjects: cosmetic talc -- granulomatosis -- pulmonary nodule -- foreign body -- inhalational pulmonary granulomatosis -- pulmonary talcosis; Internal medicine -- Periodicals; Medical care -- Periodicals; 616.005
• DOI: 10.1177/2324709617728527
• Languages: English
• ISSNs: 2324-7096

Abstract

Inhalation of cosmetic talc can lead to pulmonary foreign-body granulomatosis, though fewer than 10 cases of inhaled cosmetic talc–related pulmonary granulomatosis have been reported in adults. We report the case of a 64-year-old man with diffuse, bilateral pulmonary nodules and ground glass opacities associated with chronic inhalation of cosmetic talc. Transbronchial biopsy showed peribronchiolar foreign-body granulomas. After cessation of talc exposure, the patient demonstrated clinical and radiographic improvement without the use of corticosteroids. This case demonstrates that a conservative approach with cessation of exposure alone, without the use of corticosteroids, can be an effective therapy in cosmetic talc–related pulmonary granulomatosis.