Large multi‐centre pilot randomized controlled trial testing a low‐cost, tailored, self‐help smoking cessation text message intervention for pregnant smokers (MiQuit). (2nd May 2017)

• Record Type: Journal Article
• Authors: Naughton, Felix; Cooper, Sue; Foster, Katharine; Emery, Joanne; Leonardi‐Bee, Jo; Sutton, Stephen; Jones, Matthew; Ussher, Michael; Whitemore, Rachel; Leighton, Matthew; Montgomery, Alan; Parrott, Steve; Coleman, Tim
• Is Part Of: Addiction. Volume 112:Number 7(2017)
• Page Start: 1238
• Page End: 1249
• Publication Date: 2017-05-02
• Subjects: mHealth -- pregnancy -- randomized controlled trial -- self‐help -- smoking cessation -- SMS text messaging; Alcoholism -- Periodicals; Drug addiction -- Periodicals; 616.86
• DOI: 10.1111/add.13802
• Languages: English
• ISSNs: 0965-2140

Abstract

Abstract: Aims: To estimate the effectiveness of pregnancy smoking cessation support delivered by short message service (SMS) text message and key parameters needed to plan a definitive trial. Design: Multi‐centre, parallel‐group, single‐blinded, individual randomized controlled trial. Setting: Sixteen antenatal clinics in England. Participants: Four hundred and seven participants were randomized to the intervention ( n = 203) or usual care ( n = 204). Eligible women were < 25 weeks gestation, smoked at least one daily cigarette (> 5 pre‐pregnancy), were able to receive and understand English SMS texts and were not already using text‐based cessation support. Intervention: All participants received a smoking cessation leaflet; intervention participants also received a 12‐week programme of individually tailored, automated, interactive, self‐help smoking cessation text messages (MiQuit). Outcome measurements: Seven smoking outcomes, including validated continuous abstinence from 4 weeks post‐randomization until 36 weeks gestation, design parameters for a future trial and cost‐per‐quitter. Findings: Using the validated, continuous abstinence outcome, 5.4% (11 of 203) of MiQuit participants were abstinent versus 2.0% (four of 204) of usual care participants [odds ratio (OR) = 2.7, 95% confidence interval (CI) = 0.93–9.35]. The Bayes factor for this outcome was 2.23. Completeness of follow‐up at 36 weeks gestation was similar in both groups; provision of self‐report smoking data was 64% (MiQuit) and 65% (usual care) and abstinence validation rates were 56% (MiQuit) and 61% (usual care). The incremental cost‐per‐quitter was £133.53 (95% CI = –£395.78 to 843.62). Conclusions: There was some evidence, although not conclusive, that a text‐messaging programme may increase cessation rates in pregnant smokers when provided alongside routine NHS cessation care.