Sex-Related Differences in the Physiology, Risk, and Outcomes of Transcatheter Aortic Valve Replacement. Issue 1 (March 2017)

• Record Type: Journal Article
• Authors: Chen, Jennifer; Hahn, Rebecca T.
• Is Part Of: Gender and the genome. Volume 1:Issue 1(2017)
• Page Start: 12
• Page End: 17
• Publication Date: 2017-03
• Subjects: aortic stenosis -- transcatheter -- surgical -- valve replacement -- sex; Sex (Biology) -- Periodicals; Genomics -- Periodicals; Sex factors in disease -- Periodicals; 616
• DOI: 10.1089/gg.2016.0004
• Languages: English
• ISSNs: 2470-2897

Abstract

Transcatheter aortic valve replacement (TAVR) is a less-invasive alternative to surgical aortic valve replacement (SAVR) for the management of symptomatic severe aortic stenosis in patients with inoperable, high, or intermediate surgical risk. Females undergoing TAVR exhibit distinct physiology and baseline characteristics from their male counterparts. Although rates of procedural complications are higher, medium-term survival appears better for females than males. These sex-based differences are discussed in depth in this review of TAVR in the female population.