CHORIORETINAL BIOPSY FOR THE DIAGNOSIS OF ENDOGENOUS ENDOPHTHALMITIS DUE TO ESCHERICHIA COLI. Issue Volume 11:Issues 1(2017:Winter) (2017)

• Record Type: Journal Article
• Authors: Cheng, Nicholas M.; Chandra, Aman; Roufail, Edward; Moodie, Jonathan J.; Yeoh, Jonathan; Allen, Penelope J.; Salinas-La Rosa, Cesar M.; Matthews, Bryan J.
• Is Part Of: Retinal cases & brief reports. Volume 11:Issues 1(2017:Winter)
• Publication Date: 2017
• Subjects: chorioretinal biopsy -- endogenous -- endophthalmitis -- Escherichia coli; Retina -- Diseases -- Periodicals; Retina -- Periodicals; Retinal Diseases -- Periodicals; Retina -- Case Reports; Retinal Diseases -- Case Reports; 617.7
• DOI: 10.1097/ICB.0000000000000281
• Languages: English
• ISSNs: 1935-1089

Abstract

Abstract : Purpose: To describe the novel use of a chorioretinal biopsy technique to confirm the microbiological diagnosis of endogenous Escherichia coli ( E. coli ) endophthalmitis, when other investigations have been proven nondiagnostic. Methods: Case report of an 82-year-old white man with endogenous endophthalmitis without a clearly identifiable source of infection. Results: After systemic cultures and multiple aqueous and vitreous samples were unable to identify a causative organism, chorioretinal biopsy of a subretinal abscess was used to confirm the microbiological diagnosis. This ensured appropriate ophthalmic and systemic treatment of infection. Conclusion: Endogenous E. coli endophthalmitis is a rare and aggressive condition usually seen in patients with insulin-dependent diabetes with concurrent urinary tract infection. This case demonstrates chorioretinal biopsy to be a viable and effective method of establishing a firm microbiological diagnosis in cases of culture-negative endophthalmitis. Abstract : Supplemental Digital Content is Available in the Text.Endogenous endophthalmitis due to Escherichia coli is a rare and aggressive condition. This case demonstrates chorioretinal biopsy to be a viable and effective method of establishing a firm microbiological diagnosis in cases of culture-negative endophthalmitis. This novel diagnostic approach allowed an appropriate ophthalmic and systemic treatment of infection.