Meningoencephalitis and otitis media in a child with Mycoplasma pneumoniae infection*. Issue 1 (1st January 2017)

• Record Type: Journal Article
• Authors: Pelkonen, Tuula; Sarajuuri, Anne; Rautanen, Tarja; Sinkkonen, Saku T.; Jero, Jussi
• Is Part Of: Acta oto-laryngologica case reports. Volume 2:Issue 1(2017)
• Page Start: 1
• Page End: 4
• Publication Date: 2017-01-01
• Subjects: Meningoencephalitis -- otitis media -- child -- Mycoplasma pneumoniae
• DOI: 10.1080/23772484.2016.1247249
• Languages: English
• ISSNs: 2377-2484

Abstract

Abstract: We report on a previously healthy 11-year-old male presenting with meningoencephalitis and otitis media. Computed tomography demonstrated opacification of the right middle ear and mastoid ear cells, but no destructive changes. Anti- Mycoplasma pneumoniae IgG and IgM were positive in serum and at high concentrations in cerebrospinal fluid (CSF), and its nucleic acid was detected in the middle ear fluid and in a throat swab, but not in CSF. EEG showed generalized slowing and right temporal sharp waves. Brain MRI imaging remained normal. After a 3-week treatment with doxycycline and a tympanostomy tube, the patient recovered, and no long-term neurological sequelae have appeared. Diagnostics and pathogenetic mechanisms in meningoencephalitis caused by M. pneumoniae are discussed.