68Ga-PSMA Uptake in Combined Hepatocellular Cholangiocarcinoma With Skeletal Metastases. (October 2017)

• Record Type: Journal Article
• Authors: Alipour, Ramin; Gupta, Sandeep; Trethewey, Scott
• Is Part Of: Clinical nuclear medicine. Volume 42:Number 10(2017)
• Publication Date: 2017-10
• Subjects: combined hepatocellular cholangiocarcinoma -- skeletal metastases -- 68Ga-PSMA PET; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000001771
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: 68 Ga-PSMA PET is a rapidly evolving imaging modality for whole-body staging of prostate cancer. We report a case of a 70-year-old man with mildly elevated prostate-specific antigen (8.1 μg/L) and clinical suspicion of prostate cancer (osteoblastic metastases on radionuclide bone scan) who was referred for 68 Ga-PSMA PET/CT for primary staging. Multiple 68 Ga-PSMA–avid skeletal foci, mostly associated with lytic changes on low-dose CT, as well as hepatic foci of avid 68 Ga-PSMA uptake, were identified. No abnormal focus of avid 68 Ga-PSMA uptake was identified in the prostate. On histopathological examination, the liver lesion proved to be combined hepatocellular cholangiocarcinoma.