Gorham-Stout Disease Affecting the Mandible: Bone Scintigraphy and Computed Tomography Findings. (October 2017)

• Record Type: Journal Article
• Authors: Park, Soo Bin; Choi, Joon Young; Kim, Soo Jeong
• Is Part Of: Clinical nuclear medicine. Volume 42:Number 10(2017)
• Publication Date: 2017-10
• Subjects: Gorham-Stout disease -- osteolysis -- 99mTc-MDP -- bone scan -- mandible; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000001800
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: We present images of a 13-year-old boy with Gorham-Stout disease affecting the mandible. Initial bone scintigraphy showed poor visualization of 99m Tc-methylene diphosphonate ( 99m Tc-MDP) uptake in the mandible body. However, abnormally increased 99m Tc-MDP uptake was noted in the bilateral mandibular rami. In the follow-up examination a year later, bone scintigraphy indicated that the disease had progressed to the bilateral mandibular rami with no uptake. In addition, massive osteolysis of the mandible was noted that had progressed since the initial computed tomography. This report suggests that bone scintigraphy could be a useful imaging tool to evaluate disease activity and determine treatment response.