The Neural Correlates of Negative Symptoms in Schizophrenia: Examples From MRI Literature. (January 2018)

• Record Type: Journal Article
• Authors: Mørch-Johnsen, Lynn; Agartz, Ingrid; Jensen, Jimmy
• Other Names: Mucci Armida guest-editor.; Nielsen Mette Ødegaard guest-editor.
• Is Part Of: Clinical EEG and neuroscience. Volume 49:Number 1(2018)
• Page Start: 12
• Page End: 17
• Publication Date: 2018-01
• Subjects: schizophrenia -- negative symptoms -- MRI -- neuroimaging -- avolition; Electroencephalography -- Periodicals; Neurosciences -- Periodicals; 616.8047547
• DOI: 10.1177/1550059417746214
• Languages: English
• ISSNs: 1550-0594

Abstract

Negative symptoms of schizophrenia have a negative impact on psychosocial functioning and disease outcome. It is therefore important to investigate the pathophysiology underlying negative symptoms as this may aid the development of better treatment. In the current article, examples from studies investigating neural correlates of negative symptoms in schizophrenia are given. Investigations using both structural and functional magnetic resonance imaging are presented at different levels of symptomatology descriptions, from the more heterogenous construct of negative symptoms to more single discrete symptoms. Some methods to improve imaging studies of negative symptoms in schizophrenia are also suggested.