Myxoinflammatory Fibroblastic Sarcoma: Clinical, Imaging, Management and Outcome in 29 Patients. Issue 1 (January 2017)

• Record Type: Journal Article
• Authors: Kumar, Rajendra; Lefkowitz, Robert A.; Neto, Afranio Dos Reis Teixeira
• Is Part Of: Journal of computer assisted tomography. Volume 41:Issue 1(2017)
• Publication Date: 2017-01
• Subjects: soft tissue sarcoma -- myxoinflammatory fibroblastic sarcoma -- acral myxoinflammatory fibroblastic sarcoma -- pigmented villonodular synovitis -- infection; Tomography -- Periodicals; Tomography -- Periodicals; Tomography; Periodicals; 616.0757
• DOI: 10.1097/RCT.0000000000000490
• Languages: English
• ISSNs: 0363-8715

Abstract

Abstract : Objective: This retrospective study was undertaken to highlight clinical and magnetic resonance imaging features of myxoinflammatory fibroblastic sarcoma. Methods: The clinical records of 29 patients (14 men and 15 women) were analyzed. Results: The soft tissue tumors involved hand, wrist, foot and ankle in 21 patients, more proximal extremities in 7 patients, and neck in 1 patient. The tumors were subcutaneous in 11 patients, and intramuscular in 15 patients. On magnetic resonance imaging, these tumors had nonspecific features suggestive of benign and malignant lesions. An unusual tumor in hand indicated infection, whereas an intraarticular knee tumor mimicked pigmented villonodular synovitis. All tumors were surgically resected. Conclusions: Myxoinflammatory fibroblastic sarcoma, a rare low-grade subcutaneous soft tissue tumor of distal extremities with high local recurrence after resection can mimic several benign and malignant lesions on histopathology and imaging. Rarely, it can arise in muscles and tendons, occur in nonacral sites, be aggressive, and even metastasize. In most cases, surgical resection with wide margins can be curative with low local recurrence.