DIFFUSE PERIPAPILLARY CHOROIDAL MELANOMA THAT EVOLVED FROM A SMALL PRESUMED CHOROIDAL NEVUS SUCCESSFULLY TREATED WITH GAMMA KNIFE RADIOTHERAPY. Issue Volume 10:Issues 4(2016:Autumn) (2016)

• Record Type: Journal Article
• Authors: Duker, Jacob S.; Duker, Jay S.
• Is Part Of: Retinal cases & brief reports. Volume 10:Issues 4(2016:Autumn)
• Publication Date: 2016
• Subjects: uveal melanoma -- choroidal nevus -- choroidal freckle -- gamma knife therapy; Retina -- Diseases -- Periodicals; Retina -- Periodicals; Retinal Diseases -- Periodicals; Retina -- Case Reports; Retinal Diseases -- Case Reports; 617.7
• DOI: 10.1097/ICB.0000000000000291
• Languages: English
• ISSNs: 1935-1089

Abstract

Abstract : Purpose: To report a case of diffuse peripapillary choroidal melanoma which began as a small choroidal nevus and was successfully treated with gamma knife radiotherapy. Methods: Observational case report. Results: A 31-year-old visually asymptomatic man presented for a routine eye examination and was noted to have a small choroidal nevus. Six years later, the lesion had become a diffuse juxtapapillary choroidal melanoma with a thickness of 1.9 mm. Given the peripapillary location of the tumor with involvement of about 6 clock hours of the disk, Leksell Gamma Knife radiotherapy was performed. At 5.5 years after radiation therapy, visual acuity remained 20/20. The lesion thickness had decreased to 1.5 mm, and there was no interval growth of any margins. Conclusion: Small choroidal nevi carry low malignant potential but still deserve photographic documentation when possible with regular follow intervals. Gamma knife radiotherapy can be considered for tumors abutting the optic nerve, especially when plaque radiotherapy may be technically difficult. Abstract : The authors report a case of an asymptomatic small choroidal nevus documented with fundus photographs. Six years later, the lesion had become a peripapillary diffuse choroidal melanoma. The lesion was successfully treated with Leksell Gamma Knife stereotactic radiosurgery and 5.5 years postradiation therapy, the visual acuity remained 20/20.