Clear cell tumor of the lung: Two case reports and a review of the literature. Issue 33 (August 2016)

• Record Type: Journal Article
• Authors: Xu, Qian; Lu, Cailuan; Li, Linlin; Xu, Kai
• Other Names: Zhang. Weisheng section editor.
• Is Part Of: Medicine. Volume 95:Issue 33(2016)
• Publication Date: 2016-08
• Subjects: case report -- clear cell tumor of the lung -- CT imaging -- differential diagnosis -- pathology; Medicine -- Periodicals; Medicine -- Periodicals; Médecine -- Périodiques; Geneeskunde; Medicine; Periodicals; Periodicals; 610.5
• DOI: 10.1097/MD.0000000000004492
• Languages: English
• ISSNs: 0025-7974

Abstract

Abstract: Background: Clear cell tumor of the lung (CCTL) is a rare and mostly benign pulmonary tumor arising from perivascular epithelioid cells. We reported 2 cases of CCTL in a 24-year-old man with chest pain and a 59-year-old man with dyspnea. Methods: Their chest CT images revealed a well-defined, homogeneous nodule located in the peripheral region of lung parenchyma. The solid nodule showed intense heterogenous postcontrast enhancement in the arterial phase and a homogenous appearance in the venous phase. The two patients underwent thoracotomy, and pathological examinations, including immunohistochemical studies revealed that both cases were benign clear cell tumors. Results: Due to the fact that only a few cases about CCTL were reported, clinicopathological aspects and radiological characteristics of this type of tumor are not well established. Conclusion: CCTL is a rare and benign primary tumor and majorly occurs in middle-aged and elder people. The finding of a small vessel extending along and partially wrapping up one side of the mass in the CT-enhanced images might be a helpful feature to differentiate CCTL from other lung neoplasms.