Treatment of Refractory Filamentary Keratitis With Autologous Serum Tears. Issue 5 (September 2017)

• Record Type: Journal Article
• Authors: Read, Sarah P.; Rodriguez, Marianeli; Dubovy, Sander; Karp, Carol L.; Galor, Anat
• Is Part Of: Eye & contact lens. Volume 43:Issue 5(2017:Sep.)
• Publication Date: 2017-09
• Subjects: Filamentary keratitis -- Keratopathy -- Aqueous tear deficiency -- Inflammation -- Autologous serum tears; Contact lenses -- Periodicals; Intraocular lenses -- Periodicals; Orthokeratology -- Periodicals; Anterior segment (Eye) -- Diseases -- Periodicals; 617.7523
• DOI: 10.1097/ICL.0000000000000217
• Languages: English
• ISSNs: 1542-2321

Abstract

Abstract : Purpose: To report a case of filamentary keratitis (FK) successfully treated with autologous serum tears and to review the pathogenesis and management of FK. Methods: Case report including high-resolution anterior segment optical coherence tomography and filament histopathology. Case Report: A 61-year-old Hispanic man presented with pain and photophobia of the right eye. He was found to have a corneal epithelial defect and a small peripheral infiltrate 4 months after Laser Assisted in situ Keratomileusis. After resolution of the epithelial defect, he developed FK. Over a 4-month period, conservative management with aggressive lubrication, lid hygiene, topical corticosteroids, topical cyclosporine, bandage contact lenses, and oral doxycycline failed to resolve the corneal filaments. Notably, treatment with 20% autologous serum tears, four times daily, led to a sustained resolution of the FK within 1 week. Conclusions: This case demonstrates the complexity of FK management and introduces autologous serum tears as a viable management option when conservative approaches to this condition fail.