Complications in using automated methods to increase clinical trial accrual. (9th August 2010)

• Record Type: Journal Article
• Authors: Fefilatyev, Sergiy; Chen, Li; Ivanovskiy, Tim V.; Hall, Lawrence O.; Goldgof, Dmitry; Greenstien, Halina; Garrett, Christopher
• Is Part Of: International journal of biomedical engineering and technology. Volume 4:Number 2(2010)
• Page Start: 134
• Page End: 150
• Publication Date: 2010-08-09
• Subjects: expert systems -- clinical trials -- accruals improvement -- difficulties -- cost -- patient screening -- web applications -- internet -- multiple trials -- e-healthcare -- electronic healthcare -- regulatory issues -- HIPAA -- data inputting -- patient eligibility -- gastrointestinal tumours; Biomedical engineering -- Periodicals; 610.28
• Languages: English
• ISSNs: 1752-6418

Abstract

This paper describes the issues involved in improving accruals for clinical trials using a web-based system. We installed a custom web-based expert system at the H. Lee Moffitt Cancer Center and Research Institute to help physicians screen patients for phase II clinical trials. The system allows physicians to screen a patient for multiple trials simultaneously. Experiments have shown that adaptation of the system into a clinical environment and the success of the system are related to the amount of time physicians are willing to spend entering data. We also found significant regulatory issues (HIPAA) that make implementation challenging.