Molecularly Imprinted High Affinity Nanoparticles for 4-Ethylphenol Sensing. (2015)

• Record Type: Journal Article
• Authors: Garcia-Mutio, D.; Guerreiro, A.; Gomez-Caballero, A.; Gutierrez-Climente, R.; Piletsky, S.; Goicolea, M.A.; Barrio, R.J.
• Is Part Of: Procedia engineering. Volume 120(2015)
• Page Start: 1132
• Page End: 1136
• Publication Date: 2015
• Subjects: 4-ethylphenol -- electrochemical sensor -- molecularly imprinted nanoparticles -- solid phase synthesis.; Engineering -- Congresses; Engineering -- Periodicals; Engineering; Conference proceedings; Periodicals; 620.005
• DOI: 10.1016/j.proeng.2015.08.821
• Languages: English
• ISSNs: 1877-7058

Abstract

Abstract: A novel sensor for 4-ethylphenol (4EP) was developed based on molecularly imprinted nanoparticles produced via the solid phase imprinting method. The nanoparticles were immobilised on the surface of a gold electrode previously modified with a self assembled monolayer of lipoic acid coupled to EDC/NHS ((1-ethyl-3-[dimethylaminopropyl]carbodiimide)/N-hydroxysuccinimide). Each step of the process was characterised by electrochemical impedance spectroscopy and cyclic voltammetry. The electrode was used to selectively determine 4EP by differential pulse voltammetry; a quite remarkable sensitivity improvement was observed in the nanoparticle-modified electrode in reference to the non modified bare gold electrode.