Absolute configuration of two novel compounds from the Talaromyces aculeatus using optical rotation, electronic circular dichroism and vibrational circular dichroism. Issue 1 (6th January 2016)

• Record Type: Journal Article
• Authors: Ding, Shuang-Shuang; Zhang, Can-Can; Shi, Wen-Si; Liang, Miao-Miao; Yang, Qin; Zhu, Hua-Jie; Li, Yan
• Is Part Of: Tetrahedron letters. Volume 57:Issue 1(2016)
• Page Start: 75
• Page End: 79
• Publication Date: 2016-01-06
• Subjects: Talaromyces aculeatus (DS-62013) -- Absolute configuration determination -- Optical rotation -- Electronic circular dichroism -- Vibrational circular dichroism; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tetlet.2015.11.066
• Languages: English
• ISSNs: 0040-4039

Abstract

Graphical abstract: Abstract: Two novel compounds (1 –2 ), together with two known compounds3 (Pinophilins B) and4 (Sch 725680) were isolated from the fermentation broth of fungus of Talaromyces aculeatus (DS-62013). Absolute configuration (AC) of compound1 was deduced by comparison of experimental and calculated optical rotation (OR), electronic circular dichroism (ECD), and vibrational circular dichroism (VCD) with those of its derivative1a . Since both OR and ECD methods cannot provide the convincible data for AC identification, and VCD was used in the AC study. The AC of compound2 was also determined.