Chemical constituents from Cynanchum paniculatum (Bunge) Kitag. (August 2015)

• Record Type: Journal Article
• Authors: Niu, Ya-Le; Chen, Xi; Wu, Yi; Jiang, Hai-Qiang; Zhang, Xue-Lan; Li, En-Tao; Li, You-Ying; Zhou, Hong-Lei; Liu, Jia-Guo; Wang, De-Yun
• Is Part Of: Biochemical systematics and ecology. Volume 61(2015)
• Page Start: 139
• Page End: 142
• Publication Date: 2015-08
• Subjects: Cynanchum paniculatum (Bunge) Kitag -- Steroidal sapogenins -- Acetophenone derivatives -- Pentacyclic triterpenoids -- Chemotaxonomic relationships; Chemotaxonomy -- Periodicals; Biochemical variation -- Periodicals; Ecology -- Periodicals; Biochemistry -- Periodicals; Ecology -- Periodicals; Chimiotaxinomie -- Périodiques; Variation biochimique -- Périodiques; Écologie -- Périodiques; 578.012
• DOI: 10.1016/j.bse.2015.06.018
• Languages: English
• ISSNs: 0305-1978

Abstract

Abstract: Twenty-nine compounds, including five acetophenone derivatives (1–5 ), three phenanthroindolizidine alkaloids (12–14 ), seven pentacyclic triterpenoids (15–21 ) and five C21 steroidal sapogenins (22–26 ), were isolated from the root of Cynanchum paniculatum (Bunge) Kitag. Their structures were determined by spectroscopic methods and comparison with reported data. Moreover, the chemotaxonomic relationships were also discussed. As a result, acetophenone derivatives, pentacyclic triterpenoids and C21 pregnane sapogenins can be recognized as chemotaxonomic markers for Cynanchum genus, and C. paniculatum has close relationships with some species of genus Cynanchum . Highlights: We studied the isolation of Cynanchum paniculatum (Bunge) Kitag and obtained twenty-nine compounds. The structures of these compounds were elucidated by spectroscopic methods. Five compounds were firstly reported from Asclepiadaceae family. Compounds7, 15–17, 19, 20 and 27 were obtained from C. paniculatum firstly for the first time. The isolated constituents exhibited the relationships between C. paniculatum and some other plants of Cynanchum genus.