Disease Burden, Characteristics, and Outcomes of Methicillin-Resistant Staphylococcus aureus Bloodstream Infection in Hong Kong. (July 2017)

• Record Type: Journal Article
• Authors: You, Joyce H. S.; Choi, Kin-wing; Wong, Tin-yau; Ip, Margaret; Ming, Wai-kit; Wong, Rity Yee-kwan; Chan, Sze-ngai; Tse, Hoi-tung; Chau, Carrie T. S.; Lee, Nelson L. S.
• Is Part Of: Asia-Pacific journal of public health. Volume 29:Number 5(2017)
• Page Start: 451
• Page End: 461
• Publication Date: 2017-07
• Subjects: methicillin-resistant Staphylococcus aureus -- bloodstream infection -- disease burden -- mortality -- cost -- Hong Kong; Public health -- Pacific Area -- Periodicals; Public health -- Asia -- Periodicals; 362.1095
• DOI: 10.1177/1010539517717365
• Languages: English
• ISSNs: 1010-5395

Abstract

We aimed to describe disease burden, characteristics, and outcomes of methicillin-resistant Staphylococcus aureus (MRSA) bloodstream infection (BSI) in Hong Kong. A retrospective, observational study was conducted in 26 Hong Kong public hospitals between January 2010 and December 2012. The primary outcome measures were 30-day mortality rate and infection-related hospital cost. Of 1133 patients reviewed, 727 (64.17%) were male, 1075 (94.88%) had health care–associated community-onset and 44 (3.88%) had hospital-onset MRSA infection. The mean age of patients was 76 (SD = 15) years, including 172 (15.18%) aged 20 to 59 years and 961 (84.8%) aged ≥60 years. The annual incidence rates in age groups of 20 to 59 years and ≥60 years were 0.96 to 1.148 per 100 000 and 22.7 to 24.8 per 100 000, respectively. The 30-day mortality was 367 (32.39%). Older patients (>79 years), chronic lung disease, and prior hospitalization were associated with increased mortality. The mean cost was US$10 565 (SD = 11 649; US$1 = HK$7.8). MRSA BSI was a significant burden in Hong Kong.