Impact of Diabetes Mellitus on Percutaneous Coronary Intervention in Chinese Patients: A Large Single-Center Data. (July 2018)

• Record Type: Journal Article
• Authors: Wang, Huanhuan; Gao, Zhan; Song, Ying; Tang, Xiaofang; Xu, Jingjing; Jiang, Ping; Jiang, Lin; Chen, Jue; Gao, Lijian; Song, Lei; Zhang, Yin; Zhao, Xueyan; Qiao, Shubin; Yang, Yuejin; Gao, Runlin; Xu, Bo; Yuan, Jinqing
• Is Part Of: Angiology. Volume 69:Number 6(2018)
• Page Start: 540
• Page End: 547
• Publication Date: 2018-07
• Subjects: percutaneous coronary angioplasty -- drug-eluting stent -- diabetes mellitus; Blood-vessels -- Diseases -- Periodicals; Cardiovascular system -- Diseases -- Periodicals; 616.13005
• DOI: 10.1177/0003319717735226
• Languages: English
• ISSNs: 0003-3197

Abstract

Aim: To investigate the impact of diabetic status on 2-year clinical outcomes in Chinese patients undergoing contemporary percutaneous coronary intervention (PCI) treatment. Methods and Results: A total of 10 724 consecutive patients underwent PCI at Fu Wai Hospital were prospectively collected. Two-year clinical outcomes were compared between patients with and without diabetes mellitus (DM). Diabetic patients had more baseline clinical risks and more extensive coronary disease. During 2-year follow-up, the rates of all-cause death, myocardial infarction (MI), revascularization, and major adverse cardiac events (MACE) were significantly higher in DM group. After multivariable-adjusted Cox regression analysis, DM was an independent risk factor for MACE but not for the individual components of MACE. After performing propensity score matching, rates of all-cause death, MI, revascularization, stroke, stent thrombosis, and MACE were not significantly different between the 2 groups, and DM was not predictive of MACE and any clinical adverse outcomes. Conclusions: Diabetic patients who underwent PCI had worse prognosis including death and repeat revascularization during 2-year follow-up, but DM was not an independent risk factor for adverse clinical outcomes.