Serum Bovine Immunoglobulin for Chemotherapy-Induced Gastrointestinal Mucositis. (May 2018)

• Record Type: Journal Article
• Authors: Arikapudi, Sowminya; Rashid, Saima; Al Almomani, Laith Adel; Treece, Jennifer; Baumrucker, Steven J.
• Is Part Of: American journal of hospice & palliative care. Volume 35:Number 5(2018)
• Page Start: 814
• Page End: 817
• Publication Date: 2018-05
• Subjects: serum bovine immunoglobulin -- mucositis -- irritable bowel syndrome -- inflammatory bowel disease -- chemotherapy -- adverse effects -- chemotherapy-induced mucositis -- therapy; Hospice care -- Periodicals; Palliative treatment -- Periodicals; 362.175
• DOI: 10.1177/1049909117735831
• Languages: English
• ISSNs: 1049-9091

Abstract

Cancer treatments including chemotherapy and radiotherapy treat cancer by targeting rapidly dividing cells. Although these forms of treatment damage rapidly dividing cancer cells, they are also toxic to the cells of the gastrointestinal tract, leading to inflammation of the mucosal layer (mucositis) and causing nausea, vomiting, diarrhea, and abdominal pain. Improvement in symptoms may allow patients to have better performance status permitting ongoing treatment and possibly a better prognosis. This article describes the pathophysiology of chemotherapy-induced mucositis and includes 3 case reports of treatment of mucositis with serum bovine immunoglobulin.