Changes in drug use patterns reported on the web after the introduction of ADF OxyContin: findings from the Researched Abuse, Diversion, and Addiction‐Related Surveillance (RADARS) System Web Monitoring Program. Issue 9 (27th June 2017)

• Record Type: Journal Article
• Authors: Vosburg, Suzanne K.; Haynes, Colleen; Besharat, Andrea; Green, Jody L.
• Is Part Of: Pharmacoepidemiology and drug safety. Volume 26:Issue 9(2017)
• Page Start: 1044
• Page End: 1052
• Publication Date: 2017-06-27
• Subjects: abuse deterrent formulations (ADFs) -- OxyContin ADF -- postmarketing surveillance -- prescription opioids -- RADARS -- web monitoring; Pharmacoepidemiology -- Periodicals; Chemotherapy -- Periodicals; Epidemiology -- Periodicals; 615.705
• DOI: 10.1002/pds.4248
• Languages: English
• ISSNs: 1053-8569

Abstract

Abstract: This qualitative study summarizes information that individuals shared online about use of OxyContin following the August 2010 introduction of the abuse deterrent formulation (ADF). Purpose: The primary objective was to study online posts that endorsed continued use of OxyContin or a switch from OxyContin to another formulation of oxycodone or another substance altogether following the introduction of the ADF. A secondary objective was to determine whether posts revealed that the ADF led to cessation of OxyContin use. Methods: Data were collected with the Researched Abuse, Diversion, and Addiction‐Related Surveillance System Web Monitoring Program, an online surveillance system that collects and organizes posts about prescription drugs from social media websites, blogs, and forums from 3Q2009 to 4Q2014 using a commercially available web platform. Results: Posts were categorized by whether they conveyed a switch to drugs other than reformulated OxyContin or a continuation of reformulated OxyContin abuse. "Switch posts" primarily discussed switching to immediate‐release opioids. "Continue abusing" posts identified tampering strategies for alternate routes of administration, oral use, and continued use although post authors were generally unhappy with the experience. No reference to OxyContin cessation as a function of the introduction of the ADF was found; however, discontinued use was discussed. Conclusions: Web Monitoring data are useful for capturing cross sections of Internet conversation reflecting reactions to new drug formulations. These data support the notion that users will gravitate to non‐ADFs generally, and to immediate‐release non‐ADF opioid formulations, specifically, as long as these options remain on the market.