A Simple Thermoplastic Substrate Containing Hierarchical Silica Lamellae for High‐Molecular‐Weight DNA Extraction. Issue 48 (8th November 2016)

• Record Type: Journal Article
• Authors: Zhang, Ye; Zhang, Yi; Burke, Jeffrey M.; Gleitsman, Kristin; Friedrich, Sarah M.; Liu, Kelvin J.; Wang, Tza‐Huei
• Is Part Of: Advanced materials. Volume 28:Issue 48(2016)
• Page Start: 10630
• Page End: 10636
• Publication Date: 2016-11-08
• Subjects: high molecular weight -- long read sequencing -- nanoscale silica -- solid‐phase extraction -- thermoplastic; Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adma.201603738
• Languages: English
• ISSNs: 0935-9648

Abstract

Abstract : An inexpensive, magnetic thermoplastic nanomaterial is developed utilizing a hierarchical layering of micro‐ and nanoscale silica lamellae to create a high‐surface‐area and low‐shear substrate capable of capturing vast amounts of ultrahigh‐molecular‐weight DNA. Extraction is performed via a simple 45 min process and is capable of achieving binding capacities up to 1 000 000 times greater than silica microparticles.