Nasal airway responses to nasal continuous positive airway pressure breathing: An in-vivo pilot study. Issue 9 (14th June 2016)

• Record Type: Journal Article
• Authors: White, David E.; Bartley, Jim; Shakeel, Muhammad; Nates, Roy J.; Hankin, Robin K.S.
• Is Part Of: Journal of biomechanics. Volume 49:Issue 9(2016)
• Page Start: 1887
• Page End: 1890
• Publication Date: 2016-06-14
• Subjects: CPAP -- Nasal cycle -- Nasal airflow partitioning -- Nasal geometry -- MRI; Animal mechanics -- Periodicals; Biomechanics -- Periodicals; Biomechanics -- Periodicals; Mécanique animale -- Périodiques; Biomécanique -- Périodiques; Electronic journals; 571.4305
• DOI: 10.1016/j.jbiomech.2016.04.034
• Languages: English
• ISSNs: 0021-9290

Abstract

Abstract: The nasal cycle, through variation in nasal airflow partitioning, allows the upper airway to accommodate the contrasting demands of air conditioning and removal of entrapped air contaminants. The purpose of this study was to investigate the influence of nasal continuous positive airway pressure (nCPAP) breathing has on both nasal airflow partitioning and nasal geometry. Using a custom-made nasal mask, twenty healthy participants had the airflow in each naris measured during normal nasal breathing followed by nCPAP breathing. Eight participants also underwent magnetic resonance imaging (MRI) of the nasal region during spontaneous nasal breathing, and then nCPAP breathing over a range of air pressures. During nCPAP breathing, a simultaneous reduction in airflow through the patent airway together with a corresponding increase in airway flow within the congested nasal airway were observed in sixteen of the twenty participants. Nasal airflow resistance is inversely proportional to airway cross-sectional area. MRI data analysis during nCPAP breathing confirmed airway cross-sectional area reduced along the patent airway while the congested airway experienced an increase in this parameter. During awake breathing, nCPAP disturbs the normal inter-nasal airflow partitioning. This could partially explain the adverse nasal drying symptoms frequently reported by many users of this therapy.